火炸药学报2025，Vol.48Issue(7)：609-616,8.DOI:10.14077/j.issn.1007-7812.202410008
响应面法优化奥克托今的合成工艺
Optimization of the Synthesis Process of Octogen by Response Surface Method
郜兴宇 1朱泰胜 1王晓洋 1王小军 2徐子帅 2李子扬 2刘永政 1赵林秀 1李永祥1
作者信息
- 1. 中北大学化学与化工学院,山西太原 030051
- 2. 甘肃银光化学工业集团有限公司,甘肃白银 730900
- 折叠
摘要
Abstract
To clarify the complex interactions of the feed ratio in the synthesis process of Octogen(HMX)and increase the content of HMX,the response surface methodology(RSM)was employed to investigate the intricate interactions.A multiple regression model was established using the ratio of raw materials(nitric acid,ammonium nitrate,acetic acid,acetic an-hydride)as input variables and the content of HMX as the response variable.The effects of each factor on the content of HMX was determined,and the process optimization was carried out based on the raw material ratios corresponding to different HMX contents,feeding process,and reaction time.The optimal conditions are as following:the raw material ratio(molar ratio)is HA∶NA∶AN∶Ac2O∶AcOH=1.00∶5.00∶3.50∶8.00∶17.50,the acetic anhydride is added to the bottom solution at a ratio of n(Ac2O)∶n(AcOH)=1∶54,and in the first feed at a ratio of n(Ac2O)∶n(HA)=4∶1.Reaction time are set as following:first stage of 30 min,second stage of 60 min,third stage of 45 min,and pyrolysis time of 30 min.Under the optimized conditions,the product yield reaches to 81.82％with the HMX content of 91.56％.Compared with the original process,the amount of acetic anhydride is reduced by 20％,the product yield is increased by 6％,and the content of HMX is improved by approximately 4％.关键词
有机化学/奥克托今/HMX/醋酐法/工艺优化/响应面法Key words
organic chemistry/Octogen/HMX/acetic anhydride method/process optimization/response surface method分类
军事科技引用本文复制引用
郜兴宇,朱泰胜,王晓洋,王小军,徐子帅,李子扬,刘永政,赵林秀,李永祥..响应面法优化奥克托今的合成工艺[J].火炸药学报,2025,48(7):609-616,8.
