结核与肺部疾病杂志2025，Vol.6Issue(4)：382-392,11.DOI:10.19983/j.issn.2096-8493.20252002
中国结核分枝杆菌微量肉汤稀释法药物敏感性试验标准化专家共识
Expert consensus on the standardization of broth microdilution method for drug susceptibility testing of Mycobacterium tuberculosis in China
摘要
Abstract
Drug resistant tuberculosis has long been a serious challenge in the field of global public health.At present,it is difficult to provide accurate and effective treatment plans for patients based solely on binary phenotypic drug sensitivity and genotypic drug sensitivity tests.The microbroth dilution drug sensitivity test based on the microplate not only covers a variety of drugs and multiple concentrations at one time,but also provides quantitative drug resistance information for the clinic,so it is receiving more and more attention.In order to use the microbroth dilution drug sensitivity test in a reasonable,scientific,and standardized manner,the Tuberculosis Basic Professional Branch of Chinese Antituberculosis Association had organized experts in relevant fields to formulate this consensus on technical characteristics,application value,standardized operation,result interpretation,and precautions in actual operation of this drug sensitivity method,and proposed 12 recommendations,aiming to provide unified guiding principles for clinical and laboratory staff who are related to tuberculosis.关键词
分枝杆菌,结核/微生物敏感性试验/微量肉汤稀释法/总结性报告(主题)Key words
Mycobacterium tuberculosis/Microbial sensitivity tests/Broth microdilution/Consensus development conferences as topic分类
医药卫生引用本文复制引用
中国防痨协会结核病基础专业分会,余方友,赵雁林..中国结核分枝杆菌微量肉汤稀释法药物敏感性试验标准化专家共识[J].结核与肺部疾病杂志,2025,6(4):382-392,11.基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025年)(GWVI-11.1-05 （2023-2025年）
GWVI-11.2-YQ52) （）
上海市临床重点专科建设项目(结核病科)(shslezdzk03001) （结核病科）
结核病专病数据库(SHDC2020CR6024)Shanghai Three year(2023-2025)Action Plan to Strengthen the Public Health System(GWVI-11.1-05,GWVI-11.2-YQ52) （SHDC2020CR6024）
Shanghai Key Clinical Specialty Construction Project(Tuberculosis)(shslezdzk03001) （Tuberculosis）
Tuberculosis-Specific Disease Database(SHDC2020CR6024) （SHDC2020CR6024）
