兰州市7～12岁健康汉族儿童肺通气功能预计值研究OA

Objective To obtain predicted values by establishing prediction equations for pulmonary ventila-tion function indicators in healthy Han children aged 7-12 years in Lanzhou.Methods From June 2023 to May 2024,a total of 2 087 healthy Han children were recruited from five administrative districts in Lanzhou,and pulmonary ventilation function was conducted using the German Jaeger Master Screen spirometer.Ten pulmonary ventilation function indicators were recorded and analyzed,including forced expiratory volume in one second(FEV1),forced vital capacity(FVC),one-second rate(FEV1/FVC),peak expiratory flow(PEF)and volume of back extrapolation(VBE).Multiple stepwise regression analysis was performed with age,height,and weight as independent variables to establish the prediction equations for pulmonary ventilation function indicators in healthy Han boys and girls aged 7-12 yesrs in Lanzhou.Results For the 7-<8,8-<9,9-<10,10-<11 age groups,boys had higher FVC and FEV1 than girls,while boys aged 9-<10,10-<11,11-<12,12-<13 had lower FEV1/FVC than girls(P<0.05).All indicators,except FEV1/FVC and VBE/FVC,were correlated with age,height,and weight(P<0.001).There was a significant positive correlation between PEF and FEV1(P<0.001).Prediction equations for pulmonary ventilation function indicators were developed separately for boys and girls.These equations allowed for the calculation of corresponding predicted values by inputting age,height,and weight,stratified by gender.Conclusion The prediction equations established in this study can calculate the predicted values of pulmonary ventilation function for children aged 7-12 years in Lanzhou based on gender,age,height,and weight.