临床肝胆病杂志2025，Vol.41Issue(7)：1266-1269,4.DOI:10.12449/JCH250706
原发性胆汁性胆管炎与肠道菌群
Primary biliary cholangitis and the gut microbiome
赵志斌 1廉哲雄1
作者信息
- 1. 南方医科大学附属广东省人民医院,广州 510080
- 折叠
摘要
Abstract
In recent years,an increasing amount of evidence has shown that intestinal flora disturbance plays a critical role in the pathogenesis of primary biliary cholangitis(PBC).Intestinal flora participates in the development and progression of PBC by modulating bile acid metabolism,affecting immune system functions,and mediating interactions within the gut-liver axis.This article summarizes the pathophysiological features of PBC,elaborates on the mechanism of action of intestinal flora in PBC,and analyzes the potential treatment strategies based on intestinal flora regulation,in order to provide new theoretical bases for the early diagnosis and precise treatment of PBC.关键词
原发性胆汁性胆管炎/肠道微生物组/胆汁酸类和盐类/免疫系统Key words
Primary Biliary Cholangitis/Gastrointestinal Microbiome/Bile Acids and Salts/Immune System引用本文复制引用
赵志斌,廉哲雄..原发性胆汁性胆管炎与肠道菌群[J].临床肝胆病杂志,2025,41(7):1266-1269,4.
