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基底细胞样毛囊错构瘤1例

任新新 张馨燕 季双双 郭玲

皮肤性病诊疗学杂志2025,Vol.32Issue(7):530-533,4.
皮肤性病诊疗学杂志2025,Vol.32Issue(7):530-533,4.DOI:10.3969/j.issn.1674-8468.2025.07.010

基底细胞样毛囊错构瘤1例

A case of basaloid follicular hamartoma

任新新 1张馨燕 1季双双 1郭玲1

作者信息

  • 1. 聊城市人民医院,山东 聊城 252000
  • 折叠

摘要

Abstract

We report a case of basaloid follicular hamartoma.A 53-year-old female patient presented with a one-year history of widespread papules on the scalp,occasionally accompanied by itching.Dermatological examination revealed numerous light brown papules,sized approximately 1~3 mm in diameter,diffusely distributed across the scalp,with the highest density in the occipi-tal region.Some papules had coalesced.No hypertrichosis or depressions on the palms and soles were observed.Histopathology of the skin lesion revealed irregular proliferation of basaloid cells,forming multiple cell nests composed of basaloid cells embedded within a fibrous matrix.The nests were irregular in shape,with no significant cellular atypia or evident mitotic figures.Peripheral cells were arranged in a palisading pattern,with no retraction spaces between the nests and sur-rounding connective tissue.Amyloid deposits were observed within the matrix.Immunohistochem-istry revealed CD34 positivity in the fibrous stromal cells surrounding the tumor;Bcl-2 expression was limited to a few basal cells at the outermost layer of the lesion.Diagnosis:basaloid follicular hamartoma.The patient did not respond well to electrolysis and cryotherapy with liquid nitrogen,and the rash continued to progress.The patient is still under follow-up.

关键词

毛囊错构瘤/基底细胞样

Key words

follicular hamartoma/basaloid

引用本文复制引用

任新新,张馨燕,季双双,郭玲..基底细胞样毛囊错构瘤1例[J].皮肤性病诊疗学杂志,2025,32(7):530-533,4.

基金项目

聊城市重点研发计划政策引导类项目(2022YDSF29) (2022YDSF29)

皮肤性病诊疗学杂志

1674-8468

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