山东科学2025，Vol.38Issue(4)：8-13,38,7.DOI:10.3976/j.issn.1002-4026.20240071
绵萆薢的化学成分研究
Studies on the chemical constituents of the Dioscorea spongiosa
摘要
Abstract
The chemical compositions of Dioscorea spongiosa were investigated using macroporous resin,MCI column chromatography,gel column chromatography and preparative liquid chromatography.The structures of the isolated compounds were identified by 1 H-NMR,13 C-NMR,ESI-MS.Ten compounds were isolated from Dioscorea spongiosa,which were identified as three aromatic compounds:diosniponol C(1),3,5-dihydroxy-4,4′-dimethoxybibenzyl(9),P-hydroxyphenyl butanone(10);two saponin analogues:methyl protodioscin(2),protogracillin(6);three diarylheptanoids:(3R,5R)-3,5-dihydroxy-1,7-bis-(4-hydroxy-3-methoxyphenyl)-heptane 3-O-β-D-glucopyranoside(3),(3R,5R)-3,5-dihydroxy-1,7-bis(4-hydroxyphenyl)heptane 3-O-β-D-glucopyranoside(4),(3R,5R)-3,5-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)heptane 3-β-D-glucopyranoside(5);one alkaloid:cyclo(l-Pro-l-Leu)(7);one sterols:β-sitosterol(8),of which compounds(3～5),(7),(9)were isolated from Dioscorea spongiosa for the first time.In this study,the chemical constituents of 70%ethanol extract of Dioscorea spongiosa were systematically isolated,which enriched the chemical composition and laid the foundation for the comprehensive development of Dioscorea spongiosa.关键词
绵萆薢/化学成分/结构鉴定Key words
Dioscorea spongiosa/chemical constituents/structural identification分类
天文与地球科学引用本文复制引用
刘伟,于金倩,董红敬,BOTIROV Erkin Khozhiakbarovich,GUSAKOVA Svetlana Dmitrievna,王晓..绵萆薢的化学成分研究[J].山东科学,2025,38(4):8-13,38,7.基金项目
科技基础资源调查专项(2018FY100702) （2018FY100702）
山东省泰山学者项目(tstp20221138) （tstp20221138）
