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新型CNT-PDMS光声换能器的制备及其声学性能与溶栓应用研究

赵攀云 李阿标 王甲琼 赵树林 任武 赵宗亚 于毅 范晓峰

生物医学工程研究2025,Vol.44Issue(3):182-188,7.
生物医学工程研究2025,Vol.44Issue(3):182-188,7.DOI:10.19529/j.cnki.1672-6278.2025.03.07

新型CNT-PDMS光声换能器的制备及其声学性能与溶栓应用研究

Preparation of a novel CNT-PDMS photoacoustic transducer and study on its acoustic performance and thrombolysis application

赵攀云 1李阿标 1王甲琼 1赵树林 2任武 1赵宗亚 3于毅 3范晓峰3

作者信息

  • 1. 新乡医学院 医学工程学院,新乡 453003
  • 2. 青岛农业大学 网络信息管理处,青岛 266109
  • 3. 新乡医学院 医学工程学院,新乡 453003||新乡医学院 河南省神经信息分析与药物智能设计国际联合实验室,新乡 453003||新乡医学院 河南省神经传感与控制工程技术研究中心,新乡 453003
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摘要

Abstract

In response to the problem of uncontrollable thickness of the photoacoustic conversion layer and complex preparation process of traditional photoacoustic transducers,we proposed a preparation method of a novel carbon nanotube polydimethylsiloxane(CNT-PDMS)photoacoustic transducers.By systematically studying the relationship between the thickness of the CNT-PDMS trans-ducer photoacoustic conversion layer and the sound pressure intensity,the structural parameters of the conversion layer were optimized.The test result of acoustic performance showed that the sound pressure intensity increased with the increase of the conversion layer thickness,and reached peak at a laser pulse repetition frequency of 4 Hz and a conversion layer thickness of 83.4 μm.The result of the ultrasound thrombolysis experiment showed that under the action of ultrasound generated by the photoacoustic transducer,the rate of blood clot dissolution increased initially and then decreased with time.Thrombolysis of 5 min could reduce the weight of blood clots by about 40%.This study provides a new technological approach for the application of photoacoustic transducers in the medical field.

关键词

光声换能器/碳纳米管/聚二甲基硅氧烷/声压强度/超声溶栓

Key words

Photoacoustic transducer/Carbon nanotube/Polydimethylsiloxane/Sound pressure intensity/Ultrasonic thrombolysis

分类

医药卫生

引用本文复制引用

赵攀云,李阿标,王甲琼,赵树林,任武,赵宗亚,于毅,范晓峰..新型CNT-PDMS光声换能器的制备及其声学性能与溶栓应用研究[J].生物医学工程研究,2025,44(3):182-188,7.

基金项目

河南省科技攻关项目(242102310480). (242102310480)

生物医学工程研究

1672-6278

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