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床旁荧光免疫层析法在ICU血药浓度监测中的临床价值

龙泽禹 寇皓 李天龙 彭志勇

实用休克杂志(中英文)2025,Vol.9Issue(2):82-86,5.
实用休克杂志(中英文)2025,Vol.9Issue(2):82-86,5.

床旁荧光免疫层析法在ICU血药浓度监测中的临床价值

Clinical application and evaluation of fluorescence immunochromatography assay for therapeutic drug mo-nitoring in ICU

龙泽禹 1寇皓 2李天龙 1彭志勇1

作者信息

  • 1. 武汉大学中南医院重症医学科||湖北省重症医学临床医学研究中心
  • 2. 武汉大学中南医院药学部
  • 折叠

摘要

Abstract

Objective To evaluate the accuracy and feasibility of fluorescence immunochroma-tography Assay in therapeutic drug monitoring in ICU clinical practice.Methods By measuring the concentrations of sodium valproate,norvancomycin,and vancomycin in the blood of ICU patients,the correlation and agreement between fluorescence immunochromatography Assay and high-performance liquid chromatography were compared.Results Compared with the gold standard high-performance liquid chromatography,fluorescence immunochromatography Assay showed good correlation and con-sistency in measuring norvancomycin and vancomycin,but poor performance in measuring sodium val-proate.Conclusions Fluorescence immunochromatography Assay demonstrated potential application value for monitoring norvancomycin and vancomycin in ICU,but further validation is still required.

关键词

荧光免疫层析法/丙戊酸钠/去甲万古霉素/万古霉素/治疗药物监测

Key words

Fluorescence immunochromatography assay/Vancomycin/Norvancomycin/Valproate/Therapeutic drug monitoring

引用本文复制引用

龙泽禹,寇皓,李天龙,彭志勇..床旁荧光免疫层析法在ICU血药浓度监测中的临床价值[J].实用休克杂志(中英文),2025,9(2):82-86,5.

基金项目

湖北省重点研发项目(项目编号:2023BCB5) (项目编号:2023BCB5)

实用休克杂志(中英文)

2096-4544

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