实用休克杂志（中英文）2025，Vol.9Issue(2)：87-90,96,5.
全身免疫炎症指数与急性心肌梗死合并心源性休克患者院内结局的相关性分析
Correlation analysis of systemic immunoinflammatory index and hospital outcomes in patients with acute myocardial infarction complicated with cardiogenic shock
摘要
Abstract
Objective To analyze the correlation between the Systemic Immune-Inflammation Index(SII)and in-hospital outcomes in patients with acute myocardial infarction-related cardiogenic shock(AMI-CS).Methods A retrospective analysis was conducted on 592 AMI-CS patients admit-ted to Qilu Hospital of Shandong University from January 2017 to December 2023.Patients were di-vided into a death group(n=178 cases)and a survival group(n=414 cases)based on in-hospital outcomes.Baseline data,laboratory parameters,and treatment information were collected.SII was calculated as platelet count × neutrophil count/lymphocyte count.Univariate and multivariate logis-tic regression analyses were performed to assess the association between SII and in-hospital mortality.Receiver operating characteristic(ROC)curves were plotted to evaluate predictive performance.Re-sults The death group exhibited significantly higher SII levels compared to the survival group(1868.81vs.1136.67,P＜0.001).Multivariate analysis identified SII as an independent predictor of in-hospital mortality in AMI-CS patients(OR=3.015,95％CI:1.977～4.596,P＜0.001).Other independent predictors included age(OR=1.038),lactate level(OR=1.150),revascularization(OR=0.408),and platelet-to-lymphocyte ratio(PLR)(OR=0.997).ROC curve analysis demon-strated that SII had an AUC of 0.704(95％CI:0.663～0.745,P＜0.001)for predicting in-hospi-tal mortality,outperforming PLR(AUC=0.553,95％CI:0.501～0.605,P=0.04).Conclusions SII is significantly associated with in-hospital mortality risk in AMI-CS patients and serves as an ef-fective inflammatory biomarker for prognosis assessment,with superior predictive value compared to the novel biomarker PLR.Monitoring SII may aid in early identification of high-risk patients and guide clinical interventions.关键词
急性心肌梗死/心源性休克/全身免疫炎症指数/炎症反应Key words
Acute myocardial infarction/Cardiogenic shock/Systemic immune inflammatory index/Inflammatory response引用本文复制引用
林惠,夏亚楠,刘湘国,刘志舟,王艳真,边圆,徐峰..全身免疫炎症指数与急性心肌梗死合并心源性休克患者院内结局的相关性分析[J].实用休克杂志（中英文）,2025,9(2):87-90,96,5.基金项目
山东省重点研发计划(项目编号:2022CXGC010504、2024CXPT089) （项目编号:2022CXGC010504、2024CXPT089）
