天津中医药2025，Vol.42Issue(8)：985-989,5.DOI:10.11656/j.issn.1672-1519.2025.08.07
独活寄生汤联合推拿治疗慢性非特异性下腰痛的临床效果及对腰背功能和血清IL-1β、IL-6、TNF-α的影响
Clinical efficacy of Duhuo Jisheng Decoction combined with Tuina for chronic nonspecific low back pain and its effects on lumbar function and serum IL-1β,IL-6,and TNF-α
摘要
Abstract
[Objective]To investigate the clinical efficacy of Duhuo Jisheng Decoction combined with Tuina in treating chronic non-specific lower back pain(CNLBP),and its impacts on lower back function and serum levels of interleukin-1β(IL-1β),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α).[Methods]A total of 126 patients with CNLBP treated in Xingtai Central Hospital were stochastically grouped into a Tuina group and a combination group using a random number table,with 63 cases in each group.The Tuina group was treated with traditional Chinese Tuina techniques,while the combination group was treated with Duhuo Jisheng Decoction combined with Tuina.Two groups were compared in terms of clinical efficacy,traditional Chinese medicine syndrome score,lower back function,serum levels of inflammatory factors(IL-1 β,IL-6,TNF-α),and incidence of adverse reactions.[Results]The total effective rate of the combination group was 95.24％,significantly higher than the 76.19％of the Tuina group(P＜0.05).After treatment,the scores of traditional Chinese medicine syndrome,back flexion/extension ratio(F/E),serum IL-1 β,IL-6,and TNF-α levels in both groups decreased,and the combination group was significantly lower than the Tuina group(P＜0.05).After treatment,peak torque(PT)and the average power under lumbar and back extension(AP)increased,and the combination group was significantly higher than the Tuina group(P＜0.05).No adverse reactions occurred in either group.[Conclusion]The combination of Duhuo Jisheng Decoction and Tuina can achieve good clinical effects in treating CNLBP,it can effectively alleviate traditional Chinese medicine syndrome,restore their lower back function,effectively inhibit the release of related inflammatory factors,control the development of the disease,and has high safety.关键词
独活寄生汤/推拿/慢性非特异性下腰痛/中医证候/腰背功能Key words
Duhuo Jisheng Decoction/Tuina/chronic non-specific lower back pain/traditional Chinese medicine syndrome/lower back function分类
医药卫生引用本文复制引用
霍艺超,赵伟然,齐欢欢,赵瑞豪..独活寄生汤联合推拿治疗慢性非特异性下腰痛的临床效果及对腰背功能和血清IL-1β、IL-6、TNF-α的影响[J].天津中医药,2025,42(8):985-989,5.基金项目
河北省卫生健康委科研基金项目(20221599) （20221599）
邢台市重点研发计划自筹项目(2023ZC102). （2023ZC102）
