中国医疗设备2025，Vol.40Issue(8)：177-182,6.DOI:10.3969/j.issn.1674-1633.20241582
磁共振定量分析在早期膝关节炎软骨损伤情况中的研究进展
Progress in Research on Magnetic Resonance Quantitative Analysis in Early Cartilage Damage of Knee Osteoarthritis
摘要
Abstract
Knee Osteoarthritis(KOA)is an irreversible degenerative disease.In the early stage,it mainly involves the cartilage,and the pathological changes of cartilage occur much earlier than its morphological changes,making conventional magnetic resonance imaging of limited value.Magnetic resonance(MR)quantitative analysis enables quantitative assessment of early articular cartilage damage based on changes in different components of the cartilage.This paper systematically reviewed the current application status of various MR quantitative imaging methods in the early diagnosis of KOA,and analyzed the advantages and limitations of different MR quantitative methods in terms of sensitivity,specificity,imaging time,and hardware requirements.It is pointed out that improvements should be made in shortening data acquisition time,improving image quality,and reducing radiofrequency energy accumulation.Additionally,the development direction of integrating this field with artificial intelligence was prospected,aiming to provide references for early intervention and efficacy monitoring of KOA.关键词
膝关节骨性关节炎(KOA)/MR定量分析/早期软骨损伤/弥散加权成像(DWI)/蛋白聚糖(PG)Key words
knee osteoarthritis(KOA)/MR quantitative analysis/early cartilage damage/diffusion-weighted imaging(DWI)/proteoglycan(PG)分类
医药卫生引用本文复制引用
边传振,吴寒,花立春,张晓军..磁共振定量分析在早期膝关节炎软骨损伤情况中的研究进展[J].中国医疗设备,2025,40(8):177-182,6.基金项目
江苏省妇幼保健协会科研项目(FYX201918) （FYX201918）
江苏卫生健康委科研项目(K2023057). （K2023057）
