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脐带间充质干细胞对奶牛乳房炎的治疗效果研究

周群 寸静宇 龚蕾 王研 赵秀霞 王涛 汪登如 黄建新

现代畜牧科技Issue(7):31-34,4.
现代畜牧科技Issue(7):31-34,4.DOI:10.19369/j.cnki.2095-9737.2025.07.009

脐带间充质干细胞对奶牛乳房炎的治疗效果研究

Study on the Effect of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Dairy Cow Mastitis

周群 1寸静宇 1龚蕾 1王研 2赵秀霞 3王涛 1汪登如 4黄建新1

作者信息

  • 1. 大理农林职业技术学院,云南 大理 671003
  • 2. 大理白族自治州动物疫病预防控制中心,云南 昆明 650201
  • 3. 大理市畜牧兽医中心,云南 大理 671003
  • 4. 云南研灵生物科技有限公司,云南 昆明 650201
  • 折叠

摘要

Abstract

In order to study the effect of umbilical cord MSCs in the treatment of mastitis in dairy cows,in this experiment,the isolated umbilical cord MSCs and antibiotics were injected into dairy cows with mastitis,and the changes of IL-6,CRP,8-OHdG,SOD,TNF-α content in serum and milk composition were compared.Results:In the serum of cows injected with MSCs,IL-6 decreased by 11.74%,CRP increased by 11.02%,8-OHdG decreased by 3.17%,SOD increased by 3.83%,TNF-α decreased by 10.61%,and the number of colonies and somatic cells in milk decreased significantly.There are differences in the changes of cytokine content in serum of dairy cows injected with antibiotics.The experiment proves that umbilical cord MSCs have the effect of treating cow mastitis,and have certain effects in inhibiting inflammation,restoring milk quality,reducing tissue damage and repairing breast tissue.

关键词

间充质干细胞/细胞因子/体细胞/菌落

Key words

mesenchymal stem cell/cytokine/somatic cell/colony

分类

农业科技

引用本文复制引用

周群,寸静宇,龚蕾,王研,赵秀霞,王涛,汪登如,黄建新..脐带间充质干细胞对奶牛乳房炎的治疗效果研究[J].现代畜牧科技,2025,(7):31-34,4.

基金项目

大理农林职业技术学院自然科学研究项目(DNLKY2023XJ02) (DNLKY2023XJ02)

现代畜牧科技

2095-9737

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