中国防痨杂志2025，Vol.47Issue(8)：976-980,5.DOI:10.19982/j.issn.1000-6621.20250124
基于舌拭子的结核分枝杆菌复合群核酸检测方法在肺结核诊断和筛查中的应用前景与挑战
The potentials and challenges of using tongue swab for Mycobacterium tuberculosis complex detection through nucleic acid amplification tests in the diagnosis and screening of pulmonary tuberculosis
摘要
Abstract
Tuberculosis(TB)remains a major global public health challenge.Etiological examination serves as a critical approach for TB diagnosis.However,some suspected pulmonary TB patients initially present with no sputum or face difficulties in providing qualified sputum specimens,limiting the effectiveness of sputum-based laboratory detection methods.Concurrently,non-sputum based diagnostic methods,such as oral swab,blood,urine,and other body fluids,has become a focus in TB diagnostic research and development.This article systematically analyzes the current research progress on tongue swab-based TB diagnosis and screening,existing challenges,and key considerations in the application of tongue swabs for TB diagnosis and screening.The aim is to provide references for technological optimization and pilot implementations across diverse scenarios.关键词
结核,肺/诊断/舌拭子/总结性报告Key words
Tuberculosis,pulmonary/Diagnosis/Tongue swab/Consensus development conference分类
医药卫生引用本文复制引用
夏辉,赵雁林..基于舌拭子的结核分枝杆菌复合群核酸检测方法在肺结核诊断和筛查中的应用前景与挑战[J].中国防痨杂志,2025,47(8):976-980,5.基金项目
Program for Tuberculosis Prevention and Control(2528) （2528）
Public Health Personal Development Support Project(01056) 结核病预防与控制项目(2528) （01056）
公卫人才培养支持项目(01056) （01056）
