中国内镜杂志2025，Vol.31Issue(7)：69-75,7.DOI:10.12235/E20240403
完全神经内镜下显微血管减压术联合神经梳理术治疗原发性三叉神经痛的临床疗效及其对预后的影响
Observation on the therapeutic effect of microsurgical vascular decompression under complete neuroendoscopy combined with nerve combing surgery in the treatment of trigeminal neuralgia and its impact on prognosis
摘要
Abstract
Objective To explore the therapeutic effect of microsurgical vascular decompression(MVD)under complete neuroendoscopy combined with nerve combing surgery in the treatment of primary trigeminal neuralgia(TN),and its impacts on prognosis.Methods 108 primary TN patients from November 2021 to November 2023 were retrospectively selected and grouped into combined group and control group based on the surgical plan,with 54 cases in each group.The control group received MVD treatment under the microscope,while the combined group received complete neuroendoscopic MVD combined with nerve combing surgery.The total effective rate,pain degree,stress indicators,quality of life,and complications were compared between the two groups.Results The total effective rate of the combined group(96.30%)was greatly higher than that of the control group(83.33%),the difference was statistically significant(P<0.05).The visual analogue scale(VAS)scores of both groups after surgery were significantly lower than those before surgery,and the combined group was lower than the control group,the differences were statistically significant(P<0.05).After surgery,the levels of norepinephrine(NE),superoxide dismutase(SOD),and cortisol(Cor)increased in both groups compared with those before surgery,but the combined group was greatly lower than that of the control group,the differences were statistically significant(P<0.05).The generic quality of life inventory-74(GQOL-74)scores in both groups after surgery were significantly higher than those before surgery,and the combined group was higher than the control group,the differences were statistically significant(P<0.05).There was no difference of the total complication rate between the two groups(P>0.05).Conclusion MVD under complete neuroendoscopy combined with nerve combing surgery in the treatment of primary TN,can relieve pain,reduce stress response and improve the quality of life of patients.It is worthy of clinical promotion and application.关键词
原发性三叉神经痛(TN)/神经内镜/显微血管减压术(MVD)/神经梳理术/疼痛程度Key words
primary trigeminal neuralgia(TN)/neuroendoscopy/microsurgical vascular decompression(MVD)/nerve combing technique/pain degree分类
医药卫生引用本文复制引用
王鹏,李庆,谢东,刘旭兰,李艳昆,王春生..完全神经内镜下显微血管减压术联合神经梳理术治疗原发性三叉神经痛的临床疗效及其对预后的影响[J].中国内镜杂志,2025,31(7):69-75,7.基金项目
保定市科学技术局项目(No:2141ZF234) （No:2141ZF234）
