中国药房2025，Vol.36Issue(15)：1841-1845,5.DOI:10.6039/j.issn.1001-0408.2025.15.04
基于循证方法学和德尔菲法构建地佐辛注射液的药物利用评价标准
Construction of drug utilization evaluation criteria for Dezocine injection based on evidence-based methodology and Delphi method
摘要
Abstract
OBJECTIVE To construct the drug utilization evaluation criteria for Dezocine injection,so as to provide reference for the rational drug use in medical institutions.METHODS On the basis of evidence methodology,relevant guidelines/expert consensus,systematic reviews/meta-analysis were consulted;the evaluation criteria framework for Dezocine injection was established after screening evidence.Delphi method was employed,whereby 28 clinicians and clinical pharmacists from secondary and above-level medical institutions across eight provinces,including Tianjin,Beijing and Shandong,were selected to participate in two rounds of questionnaire surveys.The final indicators were determined based on the experts'enthusiasm coefficient,authority coefficient,and degree of coordination.RESULTS The effective recovery rate of questionnaire was 100%in the first round and 92.86%in the second round;expert authority coefficient was 0.82 in the first round and 0.81 in the second round;the coordination degree of experts in the first round was 0.29,and in the second round was 0.31(P＜0.001).Drug utilization evaluation standard system for Dezocine injection was formed finally,including three dimensions of medication indications,medication process and medication results,with a total of 11 first-level indicators(such as indications,usage and dosage)and 33 second-level indicators(such as labor analgesia and the management of severe pain following major or moderate surgeries combined with other analgesic drugs).The average importance scores for each indicator ranged from 4.08 to 5.00 points,with an overall average score of 4.61 points and coefficient of variation ranging from 0 to 0.19.CONCLUSIONS The drug utilization evaluation criteria for Dezocine injection established based on evidence-based methodology and Delphi method is authoritative and scientific,which provides a reference for subsequent evaluation of the rationality of clinical medication.关键词
地佐辛注射液/药物利用/评价标准/循证方法学/德尔菲法Key words
Dezocine injection/drug utilization/evaluation criteria/evidence-based methodology/Delphi method分类
医药卫生引用本文复制引用
郭媛媛,王超,秦寅鹏,张弋,卜一珊..基于循证方法学和德尔菲法构建地佐辛注射液的药物利用评价标准[J].中国药房,2025,36(15):1841-1845,5.基金项目
白求恩公益基金会天津药学中青年科研项目(No.TJYX2023-11) （No.TJYX2023-11）
