中国医学前沿杂志（电子版）2025，Vol.17Issue(6)：28-33,6.DOI:10.12037/YXQY.2025.06-04
肠道菌群与药物性肝损伤
Intestinal microbiota and drug-induced liver injury
摘要
Abstract
Intestinal microbiota is an indispensable new"functional organ"of the body,and intestinal microbiota is an important part of it.Researches have indicated that intestinal microbiota imbalance exists in several chronic liver diseases,and the modulation of intestinal microbiota is conducive to the rehabilitation of liver conditions.Drug-induced liver injury(DILI)is a common liver disease.Studies have demonstrated that alterations in intestinal microbiota are implicated in the occurrence and development of DILI.In this article,the effects of drugs on intestinal microbiota,the influence of the intestinal microbiota in DILI,and the diagnosis and treatment strategies of DILI targeting intestinal microbiota are reviewed,which will provide references for the treatment or prevention of DILI.关键词
肠道菌群/药物性肝损伤/诊断/治疗Key words
Intestinal microbiota/Drug-induced liver injury/Diagnosis/Treatment引用本文复制引用
李艳,师安怡,邢卉春..肠道菌群与药物性肝损伤[J].中国医学前沿杂志（电子版）,2025,17(6):28-33,6.基金项目
国家重点研发计划(2022YFC2304500) （2022YFC2304500）
北京市科技计划(Z221100007422002) （Z221100007422002）
国家重点研发计划(2021YFC2301800) （2021YFC2301800）
首都卫生发展科研专项(首发2024-1-2181) （首发2024-1-2181）
肝胆相照公益基金(iGandanF-1082023-GSH011) National Key Research and Development Program of China(2022YFC2304500) （iGandanF-1082023-GSH011）
Beijing Municipal Science and Technology Plan(Z221100007422002) （Z221100007422002）
National Key Research and Development Program of China(2021YFC2301800) （2021YFC2301800）
Capital's Funds for Health Research and Development(2024-1-2181) （2024-1-2181）
Gan Dan Xiang Zhao Public Welfare Fund(iGandanF-1082023-GSH011) （iGandanF-1082023-GSH011）
