中国医学前沿杂志（电子版）2025，Vol.17Issue(6)：34-39,6.DOI:10.12037/YXQY.2025.06-05
药物性肝损伤临床转归相关危险因素
Risk factors for clinical outcomes of drug-induced liver injury
摘要
Abstract
Drug-induced liver injury(DILI)presents a significant diagnostic and therapeutic challenge due to its diverse clinical features and pathological manifestations,especially its overlap with autoimmune hepatitis(AIH).This article reviewed the clinical outcomes of DILI and the associated influencing factors,explored the application and limitations of laboratory indicators,imaging,and pathological assessments in diagnosis and treatment,and proposes early identification and management strategies for high-risk patients who might progress to AIH.These insights aim to provide a scientific basis for the precise diagnosis and personalized treatment of DILI.关键词
药物性肝损伤/自身免疫性肝损伤/药物诱导性自身免疫性肝损伤/病理学评估/临床转归Key words
Drug-induced liver injury/Autoimmune liver injury/Drug-induced autoimmune liver injury/Pathological assessment/Clinical outcomes引用本文复制引用
师安怡,孙磊,邢卉春..药物性肝损伤临床转归相关危险因素[J].中国医学前沿杂志（电子版）,2025,17(6):34-39,6.基金项目
北京市科技计划(Z221100007422002) （Z221100007422002）
首都卫生发展科研专项(首发2024-1v2181) （首发2024-1v2181）
肝胆相照公益基金(iGandaF-1082023-GSH011) Beijing Science and Technology Program(Z221100007422002) （iGandaF-1082023-GSH011）
Capital Health Development Scientific Research Special Project(2024-1-2181) （2024-1-2181）
Liver and Gallbladder Solidarity Public Welfare Fund(iGandaF-1082023-GSH011) （iGandaF-1082023-GSH011）
