中国药业2025，Vol.34Issue(15)：15-18,4.DOI:10.3969/j.issn.1006-4931.2025.15.002
深圳市化妆品不良反应流行特征分析与监管监测机制优化思考
Epidemiological Characteristics of Adverse Cosmetic Reactions in Shenzhen and Consider-ations for Optimizing the Supervision and Monitoring Mechanism
摘要
Abstract
Objective To summarize the epidemiological characteristics of adverse cosmetic reactions(ACRs)in Shenzhen,and to provide a reference for optimizing ACR regulatory monitoring work.Methods A total of 121 suspected cases(involving 141 types of cosmetics)of ACRs induced by the use of cosmetics(kincare cosmetics,beauty modification cosmetics,cleansing cosmetics)admitted to the Dermatology of Shenzhen Center for Chronic Disease Control from October 15,2023 to April 15,2024 were collected.The epidemiological characteristics and related risk factors of ACRs were analyzed,and targeted suggestions for optimizing the ACR supervision and monitoring mechanism were proposed.Results The collected ACRs were all general ACRs.Among 121 ACRs,females accounted for 96.69%and males accounted for 3.31%;the onset age was in the range of 20-49 years old(90.91%),with the highest incidence of 52.07%in the range of 20-29 years old;the most common type of ACR was cosmetic contact dermatitis(84.30%),followed by cosmetic acne(12.40%)and cosmetic cheilitis(3.31%);ACRs mostly occurred within 2 weeks of using cosmetics(95.03%),with 43.80%occurring on the day of using cosmetics;most of the cosmetics were purchased online(66.66%),followed by purchased from shopping malls(13.48%)and beauty and hairdressing institutions(7.80%);ACRs involved eighty-nine domestic cosmetics(63.12%),fifty-one imported cosmetics(36.17%),and one unregistered cosmetic(0.71%);all the basic information of cosmetics could be obtained,only six cases carrying suspicious cosmetics for medical treatment,and thirty cases could not obtain information of cosmetics stores.It is suggested to strengthen the accuracy of online cosmetics information disclosure and the supervision of self-media sales of cosmetics,take measures to enhance the monitoring awareness of consumers and medical institutions,improve the quantity and quality of ACR reports,increase the sampling inspection of online cosmetics,and optimize the ACR monitoring system.Conclusion The risk of ACRs is controllable in general.ACRs are more common in young and middle-aged women and have a higher incidence in contact dermatitis.Most of the patients did not have the habit of carrying products for medical treatment,and some cannot obtain information of purchasing stores,so the accuracy of cosmetics information cannot be guaranteed.It is still necessary to strengthen public education and improve supervision and monitoring mechanism.关键词
化妆品不良反应/流行特征/风险控制/监管监测机制Key words
adverse cosmetic reaction/epidemiological characteristics/risk control/supervision and monitoring mechanism分类
医药卫生引用本文复制引用
李祥子,黄树宏,关杨,赖舒坤,钟天华,左丽..深圳市化妆品不良反应流行特征分析与监管监测机制优化思考[J].中国药业,2025,34(15):15-18,4.基金项目
广东省药品监督管理局科技创新项目[2022TDB68]. （）
