中国医院用药评价与分析2025，Vol.25Issue(7)：795-800,6.DOI:10.14009/j.issn.1672-2124.2025.07.005
奥马环素研究文献计量可视化分析
Visual Analysis of Literature Metrics on Omadacycline
摘要
Abstract
OBJECTIVE:To explore the current status and frontier hotspots of pharmacology and clinical research of omadacycline,and to provide reference and evidence-based basis for the clinical application.METHODS:The Web of Science core database was searched,with"Omadacycline""Nuzyra"as the key words,literature related to omadacycline published from the database establishment to Mar.3rd,2024 were collected.The data were visualized and analyzed by using VOSviewer 1.6.20 and CiteSpace 6.3.R1 software.RESULTS:After screening,289 articles were included.A total of 47 countries/regions participated into the research on omadacycline.The country with the highest number of publications was the United States.The research institution with the most publications was Paratek Company.The author with the most publications was Evan Tzanis.The journal Antimicrobial Agents and Chemotherapy had the highest number of publications and citation frequency.The most influential article in this research field was published by Ann B.Macone from the United States in 2014,titled In Vitro and In Vivo Antibacterial Activities of Omadacycline,a Novel Aminomethylcycline,which was cited 148 times.The current research hotspots in this field mainly focus on the evaluation of the efficacy and safety of omadacycline in the treatment of community-acquired bacterial pneumonia,acute bacterial skin and skin structure infection,as well as clinical randomized controlled studies in the treatment of bacterial infection in comparison with tigecycline and other drugs.The efficacy and safety of omacycline in off-label use and in combination with other drugs,and how to slow down the development of omacycline-resistant bacteria are the future research directions in this field.CONCLUSIONS:Omacycline,as a new type of aminomethyltetracycline antibacterial drug,has seen a rapid growth in research.Bibliometric analysis helps to clarify its research hotspots and evolving trends,providing evidence-based support for rational clinical drug use and the expansion of new indications.关键词
奥马环素/文献计量学/VOSviewer/CiteSpaceKey words
Omadacycline/Bibliometrics/VOSviewer/CiteSpace分类
医药卫生引用本文复制引用
孟超,陈姣姣,陈柯宇,程诗淇,董亚琳..奥马环素研究文献计量可视化分析[J].中国医院用药评价与分析,2025,25(7):795-800,6.基金项目
陕西省创新能力支撑计划(No.2023-CX-PT-43) （No.2023-CX-PT-43）
