肿瘤药学2025，Vol.15Issue(3)：329-336,8.DOI:10.3969/j.issn.2095-1264.2025.03.05
CD19 CAR-T细胞治疗老年复发难治性套细胞淋巴瘤合并慢性肾脏病患者1例及文献复习
CD19 CAR-T therapy for an elderly patient with relapsed/refractory mantle cell lymphoma and chronic kidney disease:a case report and literature review
周亦星 1刘俊 1李启英 1刘耀1
作者信息
- 1. 重庆大学附属肿瘤医院,重庆,400030
- 折叠
摘要
Abstract
Mantle cell lymphoma(MCL)is a special subtype of non Hodgkin's B-cell lymphoma,characterized by both invasiveness and inertness.This article reports a case of a patient with relapsed/refractory MCL complicated with chronic kidney disease(CKD).The patient achieved complete remission after receiving CD19-targeted chimeric antigen receptor T-cell(CAR-T)immunotherapy.Through clinical analysis of the case and systematic literature review,the study aims to provide evidence-based medical support for personalized comprehensive treatment strategies for relapsed/refractory MCL.关键词
套细胞淋巴瘤/CAR-T/慢性肾脏病/肾功能不全Key words
Mantle cell lymphoma/CAR-T/Chronic kidney disease/Renal insufficiency分类
医药卫生引用本文复制引用
周亦星,刘俊,李启英,刘耀..CD19 CAR-T细胞治疗老年复发难治性套细胞淋巴瘤合并慢性肾脏病患者1例及文献复习[J].肿瘤药学,2025,15(3):329-336,8.
