植物遗传资源学报2025，Vol.26Issue(8)：1516-1530,15.DOI:10.13430/j.cnki.jpgr.20241009002
泛素化调控植物免疫反应研究进展
Advances in Ubiquitination-mediated Regulation of Plant Immune Responses
摘要
Abstract
Fungal diseases constitute one of the key factors in crop yield reduction,posing a serious threat to global agricultural production and food security.When plants are attacked by pathogenic fungi,their defense mechanisms primarily involve the complex regulation of disease resistance related protein synthesis and post-translational modifications.In recent years,the role of ubiquitination in regulating plant immune responses has gained significant prominence in plant pathology and molecular biology.Ubiquitination,as a critical post-translational modification mechanism,participates in pattern recognition receptors(PRRs)-mediated signal transduction pathways.It influences receptor endocytosis,degradation,and recycling,thereby enhancing the plant's ability to recognize pathogens.Furthermore,ubiquitination interacts with plant hormone signaling pathways to collectively regulate disease resistance.As a central component of the ubiquitination process,the diversity and specificity of E3 ubiquitin ligases enable precise immune response modulation in plants.This review mainly introduces the reaction process of the ubiquitin-proteasome system and focuses on the regulatory role of protein ubiquitination in plant immune responses,as well as the functional studies of ubiquitin ligases in plants' response to pathogen infection.The aim is to provide new strategies and technical means for a deeper understanding of the mechanisms regulating plant resistance and for breeding crop varieties with enhanced resistance.Investigating ubiquitination in the context of plant immune responses is of great significance for advancing this field.关键词
植物免疫/泛素化修饰/E3泛素连接酶Key words
plant immunity/ubiquitination modification/E3 ubiquitin ligases引用本文复制引用
郭铭,王化俊,司二静,王燕绣,姚立蓉,汪军成,张宏,李葆春,孟亚雄,马小乐..泛素化调控植物免疫反应研究进展[J].植物遗传资源学报,2025,26(8):1516-1530,15.基金项目
国家大麦青稞产业技术体系(CARS-05-02A-02) （CARS-05-02A-02）
国家自然科学基金(32160496,32460517) （32160496,32460517）
甘肃省教育厅产业支撑计划(2021CYZC-12)China Agriculture Research System of MOF and MARA(CARS-05-02A-02) （2021CYZC-12）
National Natural Science Foundation of China(32160496,32460517) （32160496,32460517）
Industry Support Program of Gansu Provincial Education Department(2021CYZC-12) （2021CYZC-12）
