中医肿瘤学杂志2025，Vol.7Issue(5)：7-13,7.DOI:10.19811/j.cnki.ISSN2096-6628.2025.09.002
基于"阳化气,阴成形"理论探讨抗肿瘤治疗相关心脏毒性的病机与治疗经验
Exploration on the Pathogenesis and Clinical Experience of Cancer Therapy-Related Cardiotoxicity Based on the Theory of"Yang Transforming into Qi,and Yin Constituting Form"
摘要
Abstract
Cancer therapy-related cardiotoxicity poses a severe challenge for cancer survivors.Based on the theory of"yang transforming into qi,and yin constituting form"in Huangdi Neijing,this paper systematically explores the etiology,pathogenesis,and differentiation and treatment strategies of cancer therapy-related cardiotoxicity in traditional Chinese medicine.Anti-tumor modalities,including chemotherapy,radiotherapy,targeted therapy,and immunotherapy,induce"pathogenic toxins"that disrupt the dynamic balance of qi,blood,yin,and yang in heart.The core pathogenesis can be summarized as"yang impairment leading to dysfunctional qi transforming,yin injury resulting in structural damage,and accumulation of turbid toxins triggering pathological changes".These three mechanisms intertwine and collectively underlie the complex clinical manifestations of cancer therapy-related cardiotoxicity.Accordingly,the authors establish"harmonizing yin and yang"as the overarching therapeutic principle.Centered on the pathological core of"yang impairment-yin injury-turbid toxins",the following treatment approaches are proposed:warming and strengthening yang qi to restore transformation function,nourishing yin and fortifying the foundation to stabilize physical structure,and resolving turbid toxins to unblock heart collateral stagnation.关键词
抗肿瘤治疗/心脏毒性/核心病机/治疗经验Key words
anti-tumor therapy/cardiotoxicity/core pathogenesis/treatment experience分类
医药卫生引用本文复制引用
胡馨雨,宗铭桐,李国栋,蔡亚芳,刘泽豪,薛鹏,朱世杰..基于"阳化气,阴成形"理论探讨抗肿瘤治疗相关心脏毒性的病机与治疗经验[J].中医肿瘤学杂志,2025,7(5):7-13,7.基金项目
国家自然科学基金面上项目资助(编号:82374536) （编号:82374536）
深圳市科技计划资助(编号:JCYJ20230807120508018). （编号:JCYJ20230807120508018）
