首页|期刊导航|Fundamental Research|Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity

Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity

Zhuo Yu Yifang Zou Shulan Han Dandan Sun Lingzhi Wang Leilei Yang Yutong Li Xuemei Zhang Jianfeng Guo

Fundamental Research2025，Vol.5Issue(3)：P.1298-1312,15.

Fundamental Research2025，Vol.5Issue(3)：P.1298-1312,15.DOI:10.1016/j.fmre.2023.05.013

Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity

Zhuo Yu ¹Yifang Zou ²Shulan Han ²Dandan Sun ³Lingzhi Wang ²Leilei Yang ²Yutong Li ²Xuemei Zhang ¹Jianfeng Guo²

作者信息

1. Department of Hepatopathy,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China
2. School of Pharmaceutical Sciences,Jilin University,Changchun 130021,China Third-Grade Laboratory of Chinese Medicine Chemistry,National Administration of Traditional Chinese Medicine,Jilin University,Changchun 130021,China
3. School of Pharmaceutical Sciences,Jilin University,Changchun 130021,China
折叠

摘要

关键词

Liver cancer/Nanoparticle/Drug delivery/Chemoimmunotherapy/Combination therapy

分类

医药卫生

引用本文复制引用

Zhuo Yu,Yifang Zou,Shulan Han,Dandan Sun,Lingzhi Wang,Leilei Yang,Yutong Li,Xuemei Zhang,Jianfeng Guo..Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity[J].Fundamental Research,2025,5(3):P.1298-1312,15.

基金项目

supported by National Natural Science Foundation of China(82222074,82074154 and 81774240) （82222074,82074154 and 81774240）

the Siming Scholar from Shanghai Shuguang Hospital(SGXZ-201904) （SGXZ-201904）

the Youth Tip-top Talent Program from Shanghai Municipal Commission of Health,the Constant-eminent Program from Shanghai Municipal Commission of Health,the Xinglin Youth Scholar from Shanghai University of Traditional Chinese Medicine （）

the Norman Bethune Program of Jilin University,China(2022B40). （2022B40）

Fundamental Research

ISSN：2096-9457

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