首页|期刊导航|Fundamental Research|A tetramethylpyrazine releasing hydrogel can potentiate CAR-T cell therapy against triple negative breast cancer by reprogramming tumor vasculatures

A tetramethylpyrazine releasing hydrogel can potentiate CAR-T cell therapy against triple negative breast cancer by reprogramming tumor vasculatures

Yan Liu Yu Hao Xiang Lv Yefei Zhang Jiahui Chen Jia Tian Xinxing Ma Yehui Zhou Liangzhu Feng

Fundamental Research2025，Vol.5Issue(3)：P.1288-1297,10.

Fundamental Research2025，Vol.5Issue(3)：P.1288-1297,10.DOI:10.1016/j.fmre.2023.05.016

A tetramethylpyrazine releasing hydrogel can potentiate CAR-T cell therapy against triple negative breast cancer by reprogramming tumor vasculatures

Yan Liu ¹Yu Hao ²Xiang Lv ¹Yefei Zhang ¹Jiahui Chen ¹Jia Tian ¹Xinxing Ma ³Yehui Zhou ⁴Liangzhu Feng²

作者信息

1. Jiangsu Key Laboratory for Molecular and Medical Biotechnology,Cancer Institute,Department of Biochemistry,College of Life Science,Nanjing Normal University,Nanjing 210023,China
2. Institute of Functional Nano&Soft Materials(FUNSOM),Jiangsu Key Laboratory for Carbon-Based Functional Materials&Devices,Soochow University,Suzhou 215123,China
3. Department of Radiology,The First Affiliated Hospital of Soochow University,Suzhou 215006,China
4. Department of General Surgery,The First Affiliated Hospital of Soochow University,Suzhou 215000,China
折叠

摘要

关键词

Chimeric antigen receptor-T cell therapy/Injectable hydrogel/Triple-negative breast cancer/Tetramethylpyrazine/Tumor vasculature reprogramming

分类

医药卫生

引用本文复制引用

Yan Liu,Yu Hao,Xiang Lv,Yefei Zhang,Jiahui Chen,Jia Tian,Xinxing Ma,Yehui Zhou,Liangzhu Feng..A tetramethylpyrazine releasing hydrogel can potentiate CAR-T cell therapy against triple negative breast cancer by reprogramming tumor vasculatures[J].Fundamental Research,2025,5(3):P.1288-1297,10.

基金项目

supports from National Natural Science Foundation of China(82103099,22077093) （82103099,22077093）

the National Research Programs from Ministry of Science and Technology(MOST)of China(2021YFF0701800,2022YFF0706500) （MOST）

the Basic Science(Natural Science)Research Projects in Higher Education Institutions in Jiangsu Province(22KJB310010) （Natural Science）

the Natural Science Foundation of Jiangsu Province(BK20220110) （BK20220110）

the Suzhou Key Laboratory of Nanotechnology and Biomedicine,the Collaborative Innovation Center of Suzhou Nano Science and Technology （）

the 111 Program from the Ministry of Education of China。（）

Fundamental Research

ISSN：2096-9457

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