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Neural connectivity biotypes:predictors of clinical outcomes and improvement patterns of iTBS treatment in adolescents and young adults with depression

Weicheng Li Yanan Yin Zerui You Min Zhang Chengyu Wang Xiaofeng Lan Siming Mai Fan Zhang Zhibo Hu Guanxi Liu Xiaoyu Chen Haiyan Liu Zhanjie Luo Yexian Zeng Yiying Chen Yifang Chen Robin Shao Hanna Lu Roger S McIntyre Yanling Zhou Yuping Ning

General Psychiatry2025，Vol.38Issue(2)：P.134-143,10.

General Psychiatry2025，Vol.38Issue(2)：P.134-143,10.DOI:10.1136/gpsych-2024-101749

Neural connectivity biotypes:predictors of clinical outcomes and improvement patterns of iTBS treatment in adolescents and young adults with depression

Weicheng Li ¹Yanan Yin ²Zerui You ¹Min Zhang ²Chengyu Wang ²Xiaofeng Lan ²Siming Mai ²Fan Zhang ¹Zhibo Hu ²Guanxi Liu ¹Xiaoyu Chen ²Haiyan Liu ²Zhanjie Luo ²Yexian Zeng ²Yiying Chen ²Yifang Chen ²Robin Shao ³Hanna Lu ⁴Roger S McIntyre ⁵Yanling Zhou ²Yuping Ning¹

作者信息

1. Department of Child and Adolescent Psychiatry,The Affiliated Brain Hospital,Guangzhou Medical University,Guangzhou,Guangdong,China The First School of Clinical Medicine,Southern Medical University,Guangzhou,Guangdong,China Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders,Guangzhou,Guangdong,China Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China,Guangzhou Medical University,Guangzhou,Guangdong,China
2. Department of Child and Adolescent Psychiatry,The Affiliated Brain Hospital,Guangzhou Medical University,Guangzhou,Guangdong,China Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders,Guangzhou,Guangdong,China Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China,Guangzhou Medical University,Guangzhou,Guangdong,China
3. State Key Laboratory of Brain and Cognitive Sciences,Department of Psychology,The University of Hong Kong,Hong Kong,China
4. Department of Psychiatry,The Chinese University of Hong Kong,Shatin,Hong Kong,China
5. Canadian Rapid Treatment Center of Excellence,Mississauga,ON,Canada Mood Disorders Psychopharmacology Unit,Poul Hansen Depression Centre,University Health Network,Toronto,ON,Canada Department of Psychiatry,University of Toronto,Toronto,ON,Canada Institute of Medical Science,University of Toronto,Toronto,ON,Canada Brain and Cognition Discovery Foundation,Toronto,ON,Canada Department of Pharmacology,University of Toronto,Toronto,ON,Canada
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摘要

关键词

default mode/depression/functional network connectivity/connectivity patterns/identification predictive factorsthis/randomised controlled trial/default mode network/intermittent theta burst stimulation itbs

分类

医药卫生

引用本文复制引用

Weicheng Li,Yanan Yin,Zerui You,Min Zhang,Chengyu Wang,Xiaofeng Lan,Siming Mai,Fan Zhang,Zhibo Hu,Guanxi Liu,Xiaoyu Chen,Haiyan Liu,Zhanjie Luo,Yexian Zeng,Yiying Chen,Yifang Chen,Robin Shao,Hanna Lu,Roger S McIntyre,Yanling Zhou,Yuping Ning..Neural connectivity biotypes:predictors of clinical outcomes and improvement patterns of iTBS treatment in adolescents and young adults with depression[J].General Psychiatry,2025,38(2):P.134-143,10.

基金项目

supported by the Guangzhou Municipal Key Discipline in Medicine(2021-2023) （2021-2023）

the Guangzhou High-level Clinical Key Specialty,the Guangzhou Research-oriented Hospital,the Innovative Clinical Technique of Guangzhou(2024-2026) （2024-2026）

the Guangdong Basic and Applied Basic Research Foundation(grant number 2022A1515011567,2020A1515110565) （grant number 2022A1515011567,2020A1515110565）

the Guangzhou Science,Technology Planning Project(grant number 202201010714,202103000032) （grant number 202201010714,202103000032）

the National Natural Science Foundation of China(grant number 82471546) （grant number 82471546）

the Guangdong College Students Innovation and Entrepreneurship Training Project(grant number S202310570038) （grant number S202310570038）

the Guangzhou Health Science and Technology Project(grant number 20231A010038) （grant number 20231A010038）

the Guangzhou Traditional Chinese Medicine and Integrated Traditional Chinese and Western Medicine Technology Project(grant number:20232A010013) （grant number:20232A010013）

the Science and Technology Plan Project of Guangzhou(2023A03J0842). （2023A03J0842）

General Psychiatry

ISSN：2096-5923

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