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Integration of pharmacodynamics,network pharmacology,and metabolomics to elucidate the effect and mechanism of Huanglian Wendan Decoction in the treatment of damp-heat syndrome in rats

Lin Wang Yi Guo Rui Liu Yan-Mei Huang Chao Liu Jie-Lin Jiang Heng-Yuan Zhang Zheng-Yun Zuo Feng-Yun Yao Yan-Kun Cui

Integrative Medicine Discovery2025,Vol.9Issue(18):P.1-13,13.
Integrative Medicine Discovery2025,Vol.9Issue(18):P.1-13,13.DOI:10.53388/IMD202509018

Integration of pharmacodynamics,network pharmacology,and metabolomics to elucidate the effect and mechanism of Huanglian Wendan Decoction in the treatment of damp-heat syndrome in rats

Lin Wang 1Yi Guo 2Rui Liu 2Yan-Mei Huang 1Chao Liu 3Jie-Lin Jiang 2Heng-Yuan Zhang 1Zheng-Yun Zuo 2Feng-Yun Yao 1Yan-Kun Cui1

作者信息

  • 1. College of Traditional Chinese Medicine,Jiangxi University of Chinese Medicine,Nanchang 330004,China
  • 2. Jiangxi Provincial Engineering Research Center of Development and Evaluation of TCM Classic Prescriptions,Jiangxi University of Chinese Medicine,Nanchang 330004,China
  • 3. Medical Affairs Department,Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China
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摘要

关键词

Huanglian Wendan Decoction/damp-heat syndrome/network pharmacology/metabolomics/oxidative stress/inflammation

分类

医药卫生

引用本文复制引用

Lin Wang,Yi Guo,Rui Liu,Yan-Mei Huang,Chao Liu,Jie-Lin Jiang,Heng-Yuan Zhang,Zheng-Yun Zuo,Feng-Yun Yao,Yan-Kun Cui..Integration of pharmacodynamics,network pharmacology,and metabolomics to elucidate the effect and mechanism of Huanglian Wendan Decoction in the treatment of damp-heat syndrome in rats[J].Integrative Medicine Discovery,2025,9(18):P.1-13,13.

基金项目

supported by the National Natural Science Foundation of China(No.82360897) (No.82360897)

Natural Science Foundation of Jiangxi Province of China(No.20212BAB216007) (No.20212BAB216007)

Administration of Traditional Chinese Medicine of Jiangxi Province of China(No.2022A328). (No.2022A328)

Integrative Medicine Discovery

3021-1670

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