首页|期刊导航|Oncology Research|VPS37A Activates the Autophagy-Lysosomal Pathway for TNFR1 Degradation and Induces NF-κB-Regulated Cell Death under Metabolic Stress in Colorectal Cancer

VPS37A Activates the Autophagy-Lysosomal Pathway for TNFR1 Degradation and Induces NF-κB-Regulated Cell Death under Metabolic Stress in Colorectal Cancer

Chuncheng Liu Xiaohan Liu Ziqi Li Yanruoxue Wei Bangdong Liu Peng Zhu Yukun Liu Ran Zhao

Oncology Research2025，Vol.33Issue(8)：P.2085-2105,21.

Oncology Research2025，Vol.33Issue(8)：P.2085-2105,21.DOI:10.32604/or.2025.065739

VPS37A Activates the Autophagy-Lysosomal Pathway for TNFR1 Degradation and Induces NF-κB-Regulated Cell Death under Metabolic Stress in Colorectal Cancer

Chuncheng Liu ¹Xiaohan Liu ¹Ziqi Li ¹Yanruoxue Wei ¹Bangdong Liu ²Peng Zhu ²Yukun Liu ³Ran Zhao³

作者信息

1. Cheeloo College of Medicine,Shandong University,Jinan,250012,China
2. Department of Pathology,Affiliated Hospital of Jining Medical University,Jining Medical University,Jining,272029,China
3. Cheeloo College of Medicine,Shandong University,Jinan,250012,China Department of Pathology,Affiliated Hospital of Jining Medical University,Jining Medical University,Jining,272029,China
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摘要

关键词

VPS37A(VPS37A subunit of ESCRT-I)/tumor necrosis factor receptor 1(TNFR1)/nuclear factor kappa-B(NF-κB)signaling/metabolic stress/lysosomal degradation/colorectal cancer(CRC)

分类

医药卫生

引用本文复制引用

Chuncheng Liu,Xiaohan Liu,Ziqi Li,Yanruoxue Wei,Bangdong Liu,Peng Zhu,Yukun Liu,Ran Zhao..VPS37A Activates the Autophagy-Lysosomal Pathway for TNFR1 Degradation and Induces NF-κB-Regulated Cell Death under Metabolic Stress in Colorectal Cancer[J].Oncology Research,2025,33(8):P.2085-2105,21.

基金项目

funded by the National Natural Science Foundation of China(81902815,81802786) （81902815,81802786）

the Natural Science Foundation of Shandong Province(ZR2023MH011,ZR2019BH044,ZR2018BH025). （ZR2023MH011,ZR2019BH044,ZR2018BH025）

Oncology Research

ISSN：0965-0407

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