首页|期刊导航|Oncology Research|3-O-Acetyl-11-Keto-β-Boswellic Acid Suppresses Colitis-Associated Colorectal Cancer by Inhibiting the NF-Kb Signaling Pathway and Remodeling Gut Microbiota

3-O-Acetyl-11-Keto-β-Boswellic Acid Suppresses Colitis-Associated Colorectal Cancer by Inhibiting the NF-Kb Signaling Pathway and Remodeling Gut Microbiota

Fang Xu Wan Li Xiang-Jin Zheng Yue Hao Yi-Hui Yang Hong Yang Sen Zhang Wan-Xin Cao Xiao-Xue Li Xu Zhang Guan-Hua Du Teng-Fei Ji Jin-Hua Wang

Oncology Research2025，Vol.33Issue(8)：P.1969-1989,21.

Oncology Research2025，Vol.33Issue(8)：P.1969-1989,21.DOI:10.32604/or.2025.062386

3-O-Acetyl-11-Keto-β-Boswellic Acid Suppresses Colitis-Associated Colorectal Cancer by Inhibiting the NF-Kb Signaling Pathway and Remodeling Gut Microbiota

Fang Xu ¹Wan Li ²Xiang-Jin Zheng ¹Yue Hao ¹Yi-Hui Yang ¹Hong Yang ¹Sen Zhang ¹Wan-Xin Cao ¹Xiao-Xue Li ¹Xu Zhang ¹Guan-Hua Du ¹Teng-Fei Ji ²Jin-Hua Wang¹

作者信息

1. The State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Science and Peking Union Medical College,Beijing,100050,China Beijing Key Laboratory of Innovative Drug Discovery and Polymorphic Druggability Research for Cerebrovascular Diseases,Chinese Academy of Medical Science and Peking Union Medical College,Beijing,100050,China
2. The State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Science and Peking Union Medical College,Beijing,100050,China
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摘要

关键词

3-O-Acetyl-11-keto-b-boswellic acid(AKBA)/colorectal cancer(CRC)/inflammation/gut microbial/NF-κB pathway

分类

医药卫生

引用本文复制引用

Fang Xu,Wan Li,Xiang-Jin Zheng,Yue Hao,Yi-Hui Yang,Hong Yang,Sen Zhang,Wan-Xin Cao,Xiao-Xue Li,Xu Zhang,Guan-Hua Du,Teng-Fei Ji,Jin-Hua Wang..3-O-Acetyl-11-Keto-β-Boswellic Acid Suppresses Colitis-Associated Colorectal Cancer by Inhibiting the NF-Kb Signaling Pathway and Remodeling Gut Microbiota[J].Oncology Research,2025,33(8):P.1969-1989,21.

基金项目

financially supported by Beijing Natural Science Foundation[7252202,25JL008,China]from Beijing Natural Science Foundation Committee （）

This work was also supported by CAMS Innovation Fund for Medical Sciences[2021-I2M-1-029,2023-12M-2-006,China]and[2021-I2M-1-028,China]from Chinese Academy of Medical Science&Peking Union Medical College(CAMS&PUMC) （CAMS&PUMC）

National Natural Science Foundation of China[81703536 and 22278443,China]from Natural Science Foundation Committee （）

International Cooperation Project of Qinghai Province[2020-HZ-803,China]from Science and Technology Department of Qinghai Province. （）

Oncology Research

ISSN：0965-0407

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