首页|期刊导航|Journal of Biomedical Research|Study of the mass balance,biotransformation,and safety of[^(14)C]IBI351 in healthy Chinese subjects

Study of the mass balance,biotransformation,and safety of[^(14)C]IBI351 in healthy Chinese subjects

Shuaishuai Wang Wen Lin Bilal Ahmed Tianqi Zhong Jun Zhao Lijun Xie Hao Feng Juan Chen Chen Zhang Peng Yan Shirui Zheng Lingge Cheng Yipeng Cheng Bei Zhu Feng Han Lulu Zhang Chen Zhou

Journal of Biomedical Research2025，Vol.39Issue(4)：P.382-393,I0014-I0016,15.

Journal of Biomedical Research2025，Vol.39Issue(4)：P.382-393,I0014-I0016,15.DOI:10.7555/JBR.38.20240254

Study of the mass balance,biotransformation,and safety of[^(14)C]IBI351 in healthy Chinese subjects

Shuaishuai Wang ¹Wen Lin ¹Bilal Ahmed ¹Tianqi Zhong ²Jun Zhao ²Lijun Xie ²Hao Feng ³Juan Chen ²Chen Zhang ⁴Peng Yan ⁴Shirui Zheng ⁵Lingge Cheng ⁵Yipeng Cheng ⁵Bei Zhu ²Feng Han ¹Lulu Zhang ¹Chen Zhou²

作者信息

1. Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases,Ministry of Education,International Joint Laboratory for Drug Target of Critical Illnesses,Key Laboratory of Cardiovascular and Cerebrovascular Medicine,School of Pharmacy,Nanjing Medical University,Nanjing,Jiangsu 211166,China
2. PhaseⅠClinical Trial Unit,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
3. Value Pharmaceutical Services Co.,Ltd.,Nanjing,Jiangsu 211806,China
4. Nuclear Medicine Department,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
5. Innovent Biologics Co.,Ltd.,Shanghai 201107,China
折叠

摘要

关键词

KRAS G12C inhibitor/IBI351/pharmacokinetics/metabolism/mass balance/radiolabel study

分类

医药卫生

引用本文复制引用

Shuaishuai Wang,Wen Lin,Bilal Ahmed,Tianqi Zhong,Jun Zhao,Lijun Xie,Hao Feng,Juan Chen,Chen Zhang,Peng Yan,Shirui Zheng,Lingge Cheng,Yipeng Cheng,Bei Zhu,Feng Han,Lulu Zhang,Chen Zhou..Study of the mass balance,biotransformation,and safety of[^(14)C]IBI351 in healthy Chinese subjects[J].Journal of Biomedical Research,2025,39(4):P.382-393,I0014-I0016,15.

基金项目

supported by funding from the 13th Five-Year Plan New Drug Creation Program—Isotope Tracer Technology Platform for Clinical Evaluation of Innovative Drugs(Grant No.2017ZX09304032 with project leaders Jun Zhao and Chen Zhou). （Grant No.2017ZX09304032 with project leaders Jun Zhao and Chen Zhou）

Journal of Biomedical Research

ISSN：1674-8301

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