BIOCELL2025，Vol.49Issue(7)：P.1265-1290,26.DOI:10.32604/biocell.2025.066223
Targeting c-Src/PKCα/MAPK/NF-κB:Salvianolic Acid A as a Protective Agent against Silica Nanoparticle-Induced Lung Inflammation
Yan-Jyun Lin 1I-Ta Lee 2Wen-Bin Wu 3Chien-Chung Yang 4Chiang-Wen Lee 5Fuu-Jen Tsai 6Hui-Ching Tseng 7Wei-Ning Lin 8Li-Der Hsiao 8Chuen-Mao Yang8
作者信息
- 1. Institute of TranslationalMedicine and New Drug Development,College ofMedicine,ChinaMedical University,Taichung,40402,Taiwan,China
- 2. School of Dentistry,College of Oral Medicine,Taipei Medical University,Taipei,11031,Taiwan,China
- 3. School of Medicine,Fu Jen Catholic University,New Taipei City,24205,Taiwan,China Graduate Institute of Biomedical and Pharmaceutical Science,Fu Jen Catholic University,New Taipei City,24205,Taiwan,China
- 4. Department of Traditional Chinese Medicine,Chang Gung Memorial Hospital at Taoyuan,Taoyuan,33378,Taiwan,China School of Traditional Chinese Medicine,College of Medicine,Chang Gung University,Taoyuan,33302,Tawan,China
- 5. Department of Nursing,Division of BasicMedical Sciences,and Chronic Diseases and Health Promotion Research Center,Chang Gung University of Science and Technology,Chiayi,61363,Taiwan,China Department of Respiratory Care,Chang Gung University of Science and Technology,Chiayi,61363,Taiwan,China Department of Orthopaedic Surgery,Chang Gung Memorial Hospital,Chiayi,61363,Taiwan,China
- 6. School of Chinese Medicine,College of Chinese Medicine,China Medical University,Taichung,40402,Taiwan,China Department of Medical Research,China Medical University Hospital,China Medical University,Taichung,40402,Taiwan,China Division of Medical Genetics,China Medical University Children’s Hospital,Taichung,40447,Taiwan,China
- 7. Research Center for Chinese Herbal Medicine,Graduate Institute of Health Industry Technology,Chang Gung University of Science and Technology,Taoyuan,33303,Taiwan,China
- 8. Graduate Institute of Biomedical and Pharmaceutical Science,Fu Jen Catholic University,New Taipei City,24205,Taiwan,China
- 折叠
摘要
关键词
Silica nanoparticles/salvianolic acid A/pulmonary inflammation/COX-2 expression/NF-κB signaling pathway分类
医药卫生引用本文复制引用
Yan-Jyun Lin,I-Ta Lee,Wen-Bin Wu,Chien-Chung Yang,Chiang-Wen Lee,Fuu-Jen Tsai,Hui-Ching Tseng,Wei-Ning Lin,Li-Der Hsiao,Chuen-Mao Yang..Targeting c-Src/PKCα/MAPK/NF-κB:Salvianolic Acid A as a Protective Agent against Silica Nanoparticle-Induced Lung Inflammation[J].BIOCELL,2025,49(7):P.1265-1290,26.基金项目
supported by the National Science and Technology Council,Taiwan[Grant number:NSTC111-2320-B-030-013] （）
as well as the Chang Gung University of Science Foundation,Taiwan[Grant number:ZRRPF6N0011]. （）
