首页|期刊导航|BIOCELL|Exacerbated Cellular Senescence in Human Dopaminergic Neurons along with an Increase in LRRK2 Kinase Activity

Exacerbated Cellular Senescence in Human Dopaminergic Neurons along with an Increase in LRRK2 Kinase Activity

Dong Hwan Ho Minhyung Lee Daleum Nam Hyejung Kim Janghwan Kim Mi Kyoung Seo Sung Woo Park Ilhong Son

BIOCELL2025，Vol.49Issue(7)：P.1225-1244,20.

BIOCELL2025，Vol.49Issue(7)：P.1225-1244,20.DOI:10.32604/biocell.2025.065486

Exacerbated Cellular Senescence in Human Dopaminergic Neurons along with an Increase in LRRK2 Kinase Activity

Dong Hwan Ho ¹Minhyung Lee ²Daleum Nam ¹Hyejung Kim ¹Janghwan Kim ²Mi Kyoung Seo ³Sung Woo Park ³Ilhong Son⁴

作者信息

1. InAm Neuroscience Research Center,Wonkwang University,Sanbon Medical Center,Sanbon-Ro,Gunpo-Si,15865,Republic of Korea
2. Stem Cell Convergence Research Center,Korea Research Institute of Bioscience and Biotechnology(KRIBB),Daejeon-Si,34141,Republic of Korea Department of Functional Genomics,KRIBB School of Bioscience,University of Science and Technology,Daejeon-Si,34113,Republic of Korea
3. Paik Institute for Clinical Research,College of Medicine,Inje University,Busan-Si,47392,Republic of Korea Department of Convergence Biomedical Science,College of Medicine,Inje University,Busan-Si,47392,Republic of Korea
4. InAm Neuroscience Research Center,Wonkwang University,Sanbon Medical Center,Sanbon-Ro,Gunpo-Si,15865,Republic of Korea Department of Neurology,Wonkwang University,Sanbon-ro,Gunpo-Si,15865,Republic of Korea
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摘要

关键词

Parkinson’s disease/Leucine rich-repeat kinase 2/cellular senescence/induced dopaminergic neuron progenitor/α-synuclein

分类

医药卫生

引用本文复制引用

Dong Hwan Ho,Minhyung Lee,Daleum Nam,Hyejung Kim,Janghwan Kim,Mi Kyoung Seo,Sung Woo Park,Ilhong Son..Exacerbated Cellular Senescence in Human Dopaminergic Neurons along with an Increase in LRRK2 Kinase Activity[J].BIOCELL,2025,49(7):P.1225-1244,20.

基金项目

supportedby a grant from the Korean Fundfor Regenerative Medicine(KFRM),which is funded by the Korean government’s Ministry of Science and ICT and the Ministry of Health&Welfare(23A0102L1 to Janghwan Kim) （KFRM）

by KRIBB Research Initiative Program(KGM5362521 to Janghwan Kim) （KGM5362521 to Janghwan Kim）

supported by a grant fromthe National Research Foundation of Korea(NRF) （NRF）

which is funded by theMinistry of Science and ICT(MSIT)of the Korean government(RS-2023-NR077070 to SungWoo Park). （MSIT）

BIOCELL

ISSN：0327-9545

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