|国家科技期刊平台
| 注册
首页|期刊导航|Neural Regeneration Research|Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer''''s disease research

Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer''''s disease research

Vikas Anil Gujjala Morteza Abyadeh Isaiah Klimek Alexander Tyshkovskiy Naci Oz JoséPedro Castro Vadim NGladyshev Jason Newton Alaattin Kaya

Neural Regeneration Research2026，Vol.21Issue(6)：P.2454-2467,14.
✕
Neural Regeneration Research2026，Vol.21Issue(6)：P.2454-2467,14.DOI:10.4103/NRR.NRR-D-24-01190

Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer''''s disease research

Vikas Anil Gujjala 1Morteza Abyadeh 2Isaiah Klimek 3Alexander Tyshkovskiy 4Naci Oz 1JoséPedro Castro 5Vadim NGladyshev 4Jason Newton 6Alaattin Kaya1

作者信息

  • 1. Department of Biology,Virginia Commonwealth University,Richmond,VA,USA Center for Integrative Life Sciences,Virginia Commonwealth University,Richmond,VA,USA Department of Biochemistry and Molecular Genetics,University of Virginia School of Medicine,Charlottesville,VA,USA
  • 2. Department of Biology,Virginia Commonwealth University,Richmond,VA,USA Department of Biochemistry and Molecular Genetics,University of Virginia School of Medicine,Charlottesville,VA,USA
  • 3. Department of Biology,Virginia Commonwealth University,Richmond,VA,USA
  • 4. Division of Genetics,Department of Medicine,Brigham and Women''s Hospital,Harvard Medical School,Boston,MA,USA
  • 5. i3S,Instituto de Investigação e Inovação em Saúde,Universidade do Porto,Porto,Portugal Aging and Aneuploidy Laboratory,IBMC,Instituto de Biologia Molecular e Celular,Universidade do Porto,Porto,Portugal
  • 6. Department of Biology,Virginia Commonwealth University,Richmond,VA,USA Center for Integrative Life Sciences,Virginia Commonwealth University,Richmond,VA,USA
  • 折叠

摘要

关键词

aging biomarkers/Alzheimer''s disease/comparative genomics/congenital diseases/Down syndrome/mouse model/mucopolysaccharidoses I/Niemann-Pick type C disease

分类

医药卫生

引用本文复制引用

Vikas Anil Gujjala,Morteza Abyadeh,Isaiah Klimek,Alexander Tyshkovskiy,Naci Oz,JoséPedro Castro,Vadim NGladyshev,Jason Newton,Alaattin Kaya..Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer''''s disease research[J].Neural Regeneration Research,2026,21(6):P.2454-2467,14.

基金项目

supported by the NIA/NIH(1K01AG060040) （1K01AG060040）

Studies performed by JN were funded by the NICHD/NIH(5R00HD096117) （5R00HD096117）

Microscopy Core Facility supported,in part,with funding from NIH-NCI Cancer Center Support Grant P30 CA016059. （）

Neural Regeneration Research

1673-5374

访问量0
|
下载量0
段落导航相关论文