Neural Regeneration Research2026，Vol.21Issue(6)：P.2442-2453,12.DOI:10.4103/NRR.NRR-D-24-00037
Machine learning identifies key cells and therapeutic targets during ferroptosis after spinal cord injury
Yigang Lv 1Zhen Li 1Lusen Shi 2Huan Jian 1Fan Yang 3Jichuan Qiu 4Chao Li 1Peng Xiao 5Wendong Ruan 1Hao Li 2Xueying Li 6Shiqing Feng 7Hengxing Zhou8
作者信息
- 1. Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China
- 2. Department of Orthopedics,Qilu Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China
- 3. Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology and Pathophysiology,School of Basic Medical Sciences,Shandong University,Jinan,Shandong Province,China Shandong University Center for Orthopedics,Advanced Medical Research Institute,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China
- 4. State Key Laboratory of Crystal Materials,Shandong University,Jinan,Shandong Province,China
- 5. Key Laboratory Experimental Teratology of the Ministry of Education,Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China
- 6. Shandong University Center for Orthopedics,Advanced Medical Research Institute,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China
- 7. Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China Department of Orthopedics,Qilu Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China Shandong University Center for Orthopedics,Advanced Medical Research Institute,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China Department of Orthopedics,The Second Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China
- 8. Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China Department of Orthopedics,Qilu Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China Shandong University Center for Orthopedics,Advanced Medical Research Institute,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China Center for Reproductive Medicine,Shandong University,Jinan,Shandong Province,China
- 折叠
摘要
关键词
bioinformatic analyses/bulk-RNA sequencing/cellular communication analysis/ferroptosis/machine learning analysis/neurological function/RNA velocity analysis/single-cell RNA sequencing/therapeutic drugs/transcription factor analysis分类
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Yigang Lv,Zhen Li,Lusen Shi,Huan Jian,Fan Yang,Jichuan Qiu,Chao Li,Peng Xiao,Wendong Ruan,Hao Li,Xueying Li,Shiqing Feng,Hengxing Zhou..Machine learning identifies key cells and therapeutic targets during ferroptosis after spinal cord injury[J].Neural Regeneration Research,2026,21(6):P.2442-2453,12.基金项目
supported by the National Natural Science Foundation of China,No.81972073(to HZ) （to HZ）
a grant from the Taishan Scholars Program of Shandong Province-Young Taishan Scholars,No.tsqn201909197(to HZ) （to HZ）
a grant from Tianjin Key Medical Discipline(Specialty)Construct Project,No.TJYXZDXK-027A(to SF) （Specialty）
a grant from Academic Expert International Innovation Summit,No.22JRRCRC00010(to SF). （to SF）
