首页|期刊导航|Neural Regeneration Research|Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow

Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow

Feiyang Jin Zhengming Tian Yuying Guan Yuning Li Yakun Gu Mengyuan Guo Qianqian Shao Yingxia Liu Xiuhai Guo Zhenzhen Quan Jia Liu Xunming Ji

Neural Regeneration Research2026，Vol.21Issue(6)：P.2421-2431,11.

Neural Regeneration Research2026，Vol.21Issue(6)：P.2421-2431,11.DOI:10.4103/NRR.NRR-D-24-00716

Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow

Feiyang Jin ¹Zhengming Tian ²Yuying Guan ²Yuning Li ²Yakun Gu ²Mengyuan Guo ²Qianqian Shao ²Yingxia Liu ²Xiuhai Guo ³Zhenzhen Quan ⁴Jia Liu ²Xunming Ji⁵

作者信息

1. Beijing Institute of Brain Disorders,Laboratory of Brain Disorders,Laboratory for Hypoxia Adaptation Translational Medicine,Ministry of Science and Technology,Collaborative Innovation Center for Brain Disorders,Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,Capital Medical University,Beijing,China Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing,China
2. Beijing Institute of Brain Disorders,Laboratory of Brain Disorders,Laboratory for Hypoxia Adaptation Translational Medicine,Ministry of Science and Technology,Collaborative Innovation Center for Brain Disorders,Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,Capital Medical University,Beijing,China
3. Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing,China
4. Key Laboratory of Molecular Medicine and Biotherapy,School of Life Science,Beijing Institute of Technology,Beijing,China
5. Beijing Institute of Brain Disorders,Laboratory of Brain Disorders,Laboratory for Hypoxia Adaptation Translational Medicine,Ministry of Science and Technology,Collaborative Innovation Center for Brain Disorders,Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,Capital Medical University,Beijing,China Department of Neurosurgery,Xuanwu Hospital,Capital Medical University,Beijing,China
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摘要

关键词

bilateral carotid artery stenosis/cerebrovascular microcirculation/chronic cerebral hypoperfusion/cognitive function/high fat-high fructose diet/hippocampus/intermittent hypoxia/mitochondrial respiratory chain/prefrontal cortex/vascular cognitive impairment and dementia

分类

医药卫生

引用本文复制引用

Feiyang Jin,Zhengming Tian,Yuying Guan,Yuning Li,Yakun Gu,Mengyuan Guo,Qianqian Shao,Yingxia Liu,Xiuhai Guo,Zhenzhen Quan,Jia Liu,Xunming Ji..Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow[J].Neural Regeneration Research,2026,21(6):P.2421-2431,11.

基金项目

supported by the Beijing Nova Program,Nos.20230484436,Z211100002121038 （）

the Chinese Institutes for Medical Research,No.CX23YQ01 （）

the National Natural Science Foundation of China,Nos.32100925,82027802 （）

Beijing-Tianjin-Hebei Basic Research Cooperation Project,No.22JCZXJC00190(all to XJ and JL). （all to XJ and JL）

Neural Regeneration Research

ISSN：1673-5374

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