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Brain insulin resistance and neuropsychiatric symptoms in Alzheimer''''s disease:A role for dopamine signaling

Anastasia Kontogianni Hongbin Yang Wenqiang Chen

Neural Regeneration Research2026，Vol.21Issue(5)：P.1995-1996,2.

Neural Regeneration Research2026，Vol.21Issue(5)：P.1995-1996,2.DOI:10.4103/NRR.NRR-D-25-00281

Brain insulin resistance and neuropsychiatric symptoms in Alzheimer''''s disease:A role for dopamine signaling

Anastasia Kontogianni ¹Hongbin Yang ²Wenqiang Chen³

作者信息

1. King’s College London,Institute of Psychiatry,Psychology and Neuroscience,London,UK
2. Department of Affiliated Mental Health Center of Hangzhou Seventh People’s Hospital,Liangzhu Laboratory,The State Key Lab of Brain-Machine Intelligence,Zhejiang University,Hangzhou,Zhejiang Province,China MOE Frontier Science Center for Brain Science&Brain-Machine Integration,School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou,Zhejiang Province,China NHC and CAMS Key Laboratory of Medical Neurobiology,Zhejiang University,Hangzhou,Zhejiang Province,China
3. Steno Diabetes Center Copenhagen,Herlev,Denmark Joslin Diabetes Center,Harvard Medical School,Boston,MA,USA
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摘要

关键词

reduced cellular response insulin/dopamine signaling/insulin resistancewhich/metabolic disorder/type diabetes mellitus/brain insulin resistance/Alzheimers disease/neuropsychiatric symptoms

分类

医药卫生

引用本文复制引用

Anastasia Kontogianni,Hongbin Yang,Wenqiang Chen..Brain insulin resistance and neuropsychiatric symptoms in Alzheimer''''s disease:A role for dopamine signaling[J].Neural Regeneration Research,2026,21(5):P.1995-1996,2.

基金项目

supported by grants from NIH T32(DK007260,to WC) （DK007260,to WC）

the Steno North American Fellowship awarded by the Novo Nordisk Foundation(NNF23OC0087108,to WC) （NNF23OC0087108,to WC）

STI2030-Major Projects(2021ZD0202700,to HY) （2021ZD0202700,to HY）

the National Natural Science Foundation of China(32241004,to HY) （32241004,to HY）

the Natural Science Foundation of Zhejiang Province of China(LR24C090001,to HY) （LR24C090001,to HY）

Key R&D Program of Zhejiang Province(2024SSYS0017,to HY) （2024SSYS0017,to HY）

CAMS Innovation Fund for Medical Sciences(2019-12M-5-057,to HY) （2019-12M-5-057,to HY）

Fundamental Research Funds for the Central Universities(226-2022-00193,to HY) （226-2022-00193,to HY）

the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2023-PT310-01,to HY)。（2023-PT310-01,to HY）

Neural Regeneration Research

ISSN：1673-5374

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