磁共振成像2025，Vol.16Issue(8)：95-99,105,6.DOI:10.12015/issn.1674-8034.2025.08.014
基于双参数磁共振成像的PI-RADS v2.1评分联合PSAD对移行带前列腺癌的诊断价值
The diagnostic value of PI-RADS v2.1 score based on biparametric magnetic resonance imaging combined with PSAD for transitional zone prostate cancer
陈维娟 1赵飞 1李新红 2王志岗 1苏贝贝 1马妮1
作者信息
- 1. 兵器工业总医院影像科,西安 710065
- 2. 兵器工业总医院肿瘤科,西安 710065
- 折叠
摘要
Abstract
Objective:To explore the diagnostic value of prostate imaging reporting and data system version 2.1(PI-RADS v2.1)score based on biparametric magnetic resonance imaging(bpMRI)combined with prostate specific antigen density(PSAD)for transitional zone prostate cancer(TZPCa).Materials and Methods:A retrospective analysis was conducted on 115 patients with prostate diseases confirmed by pathology,and patients were divided into TZPCa group and benign prostatic hyperplasia(BPH)groups.The MRI images were scored according to PI-RADS v2.1,univariate and multivariate logistic regression analyses were performed on the patients'age,prostate volume(PV),total prostate specific antigen(tPSA),the ratio of free PSA to tPSA(fPSA/tPSA),PSAD and PI-RADS v2.1 score.The diagnostic efficacy of PI-RADS V2.1,PSAD and combined diagnosis for TZPCa was analyzed by receiver operating characteristic(ROC)curve,and the area under the curve(AUC)was calculated.Results:tPSA,fPSA/tPSA,PSAD,and PI-RADS v2.1 scores were statistically significant between TZPCa group and BPH group(P<0.05);PI-RADS v2.1 score and PSAD were independent predictors of TZPCa;the AUC values of PI-RADS v2.1 score,PSAD and combined model for diagnosing TZPCa are 0.916[95%confidence interval(CI):0.864 to 1.000],0.812(95%CI:0.702 to 0.921),and 0.952(95%CI:0.903 to 1.000)respectively.The combined model have the best diagnostic performance.Conclusions:The combination of PI-RADS v2.1 score and PSAD improves the diagnostic value for TZPCa and reduces unnecessary biopsy.关键词
前列腺癌/磁共振成像/前列腺特异性抗原密度/前列腺影像报告和数据系统Key words
prostate cancer/magnetic resonance imaging/prostate specific antigen density/prostate imaging reporting and data system分类
医药卫生引用本文复制引用
陈维娟,赵飞,李新红,王志岗,苏贝贝,马妮..基于双参数磁共振成像的PI-RADS v2.1评分联合PSAD对移行带前列腺癌的诊断价值[J].磁共振成像,2025,16(8):95-99,105,6.
