广州化学2025，Vol.50Issue(4)：25-32,8.DOI:10.16560/j.cnki.gzhx.20250409
磁性聚乙二醇修饰的氧化石墨烯/水滑石纳米材料制备及对血红蛋白的选择性吸附
Preparation and Selective Adsorption on Hemoglobin of Magnetic PEGylated Graphene Oxide/LDHs Nanomaterial
周珊珊 1李佳霖 1黄月文 2王斌2
作者信息
- 1. 中国科学院广州化学研究所,广东 广州 510650||中国科学院新型特种精细化学品工程实验室,广东 广州 510650
- 2. 中国科学院广州化学研究所,广东 广州 510650||中国科学院新型特种精细化学品工程实验室,广东 广州 510650||国科广化韶关新材料研究院,广东 南雄 512400||国科广化(南雄)新材料研究院有限公司,广东 南雄 512400||中国科学院大学,北京 100049
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摘要
Abstract
The magnetic composites shortly as Fe3O4@DA/GO-PEG-LDHs was prepared by self-assembly of Fe3O4 nano-particles and exfoliated Mg-Al layer double hydroxide(LDHs)on the polyethylene glycol(PEG)grafted graphene oxide(GO).TG and FT-IR tests showed that PEG was successfully modified on GO,and VSM results showed that the material was superparamagnetic.The adsorption test reveals that GO-PEG-LDHs exhibits an adsorption efficiency of 95.9%for hemoglobin(Hb)and 18.33%for bovine serum albumin(BSA).The adsorption of Hb follows the Langmuir model,with an ultrahigh adsorption capacity of 48309.18 mg/g.Meanwhile,the adsorbed Hb can be efficiently recovered through elution with a 50 mM Tris-HCl buffer,with an elution efficiency of 85.77%.Circular dichroism(CD)spectra and SDS-PAGE test indicate its favorable biocompatibility and potential for practical applications.关键词
氧化石墨烯/磁性纳米材料/血红蛋白/选择性吸附/生物相容性Key words
graphene oxide/magnetic nanomaterials/hemoglobin/selective adsorption/biocompatibility分类
化学化工引用本文复制引用
周珊珊,李佳霖,黄月文,王斌..磁性聚乙二醇修饰的氧化石墨烯/水滑石纳米材料制备及对血红蛋白的选择性吸附[J].广州化学,2025,50(4):25-32,8.
