临床输血与检验2025，Vol.27Issue(4)：456-461,6.DOI:10.3969/j.issn.1671-2587.2025.04.004
自体单采富血小板血浆与玻璃酸钠治疗膝骨关节炎短期疗效的对比分析
Comparative Analysis of Short-term Efficacy of Autologous Apheresis Platelet-rich Plasma and Hyaluronic Acid in the Treatment of Knee Osteoarthritis
摘要
Abstract
Objective To investigate the therapeutic effects of intra-articular injection of autologous apheresis platelet-rich plasma(PRP)and hyaluronic acid(HA)in the kenn of people with knee osteoarthritis(KOA).Methods From January 2022 to June 2023,60 patients with KOA were randomly divided into two groups of intra-articular HA and PRP.The patients of the two groups were followed up for three months and different outcomes were recorded.The visual analog scale(VAS)scores,McMaster index(WOMAC)and Lysholm scores of knee function evaluated all patients at rest and during movements.Measurements were taken at the beginning,the first month treatmen and the third month of treatment.Results In both groups of patients,at 1 month and 3 months after treatment,the VAS pain score and WOMAC score were lower than the baseline value(P＜0.05),while the Lysholm score was higher than the baseline value(P＜0.05).The change at three months of treatment was more significant than that at one month of treatment(P＜0.05).Moreover,the change in scores in PRP group were more significant than those in HA group(P＜0.05).Conclusion In terms of short-term pain relief and functional improvement in patients with KOA,autologous apheresis PRP treatment is superior to HA.关键词
膝骨关节炎/自体单采富血小板血浆/玻璃酸钠/功能评分Key words
Knee osteoarthritis/Autologous apheresis platelet-rich plasma/Hyaluronic acid/Functionality scoring分类
医药卫生引用本文复制引用
张新萍,马红霞,王皓,黄象艳..自体单采富血小板血浆与玻璃酸钠治疗膝骨关节炎短期疗效的对比分析[J].临床输血与检验,2025,27(4):456-461,6.基金项目
本课题受山东省济南市临床医学科技创新计划项目(No.202225073)资助 （No.202225073）
