临床误诊误治2025，Vol.38Issue(15)：32-37,6.DOI:10.3969/j.issn.1002-3429.2025.15.007
Tomita评分对脊柱转移癌患者中位生存时间的预测价值
Predictive Value of Tomita Score in the Median Survival Time of Patients with Spinal Metastatic Carcinoma
摘要
Abstract
Objective To explore the predictive value of Tomita score for the median survival time of patients with spinal metastatic carcinoma and to analyze the related factors influencing the median survival time.Methods A total of 146 patients with spinal metastatic carcinoma who visited the hospital and received treatment from January 2020 to June 2022 were selected.The general information of the patients and Tomita score information were collected,and they were followed up for 18 months to statistically analyze the survival status of the patients.The prognosis of patients with different Tomita scores were compared and its predictive value for the median survival time was analyzed.Multivariate logistic regression analysis was performed to identify the relevant factors affecting the median survival time of patients.Results There were no significant differences in patients with different with respect to age,primary tumor location,metastatic disease course,number of vertebrae involved,neurological function and Tomita score(P>0.05).The median survival time of patients with different Tomita scores during follow-up was basically consistent with the survival time indicated by the Tomita scale.The coincidence rates of expected survival time were 96.25%,89.58%and 83.33%respectively,and showed a decreasing trend with the decrease of Tomita score(P<0.05).Both the baseline alkaline phosphatase(ALP)and Ca2+levels of the patients with different Tomita scores were elevated,and were consistent with the changing trend of the Tomita score.After corresponding treatments were given based on the Tomita score,there was no change in the ALP and Ca2+levels of patients in the Tomita score>8 group(P>0.05).The levels of ALP and Ca2+in patients with Tomita scores ranging from 5 to 8 and those with Tomita scores≤4 were both decreased,and the levels were even lower in the Tomita score≤4 group(P<0.05,P<0.01).The quality of life scores showed a decreasing trend in the Tomita score>8 group,the Tomita score 5-8 group and the Tomita score≤4 group(P<0.05).Age was a protective factor for the survival time(<3 months or<12 months)of patients with spinal metastatic carcinoma.Male gender,long course of primary tumor,and Tomita score were risk factors,and long course of spinal metastatic carcinoma was a risk factor for patients with survival time<3 months.Conclusion The Tomita score has a relatively high coincidence rate in predicting the survival time of patients with spinal metastatic carcinoma.关键词
脊柱转移癌/Tomita评分/碱性磷酸酶/中位生存时间/生活质量/预测/危险因素Key words
spinal metastatic carcinoma/Tomita score/alkaline phosphatase/median survival time/quality of life/prediction/risk factors引用本文复制引用
任梦,董敏,黄春燕,沈莹,熊艳娟..Tomita评分对脊柱转移癌患者中位生存时间的预测价值[J].临床误诊误治,2025,38(15):32-37,6.基金项目
湖北省卫生健康委科研项目指导性项目(WJ2023F010) （WJ2023F010）
