肿瘤预防与治疗2025，Vol.38Issue(8)：696-702,7.DOI:10.3969/j.issn.1674-0904.2025.08.005
小视野弥散加权成像在头颈部肿瘤转移性颈部淋巴结中的应用价值
Application of Reduced Field-of-View Diffusion-Weighted Imaging in Me-tastatic Cervical Lymph Nodes from Head and Neck Cancer
摘要
Abstract
Objective:To compare the efficacy of reduced field-of-view diffusion-weighted imaging(rFOV-DWI)versus full field-of-view diffusion-weighted imaging(fFOV-DWI)for detecting metastatic cervical lymph nodes in head and neck cancer.Methods:Imaging data from 80 patients with metastatic cervical lymph nodes due to head and neck cancer were retrospectively analyzed.All patients underwent rFOV-DWI and fFOV-DWI before treatment.Two radiologists inde-pendently evaluated diffusion-weighted imaging(DWI)images in a blinded manner for subjective assessment of overall image quality,sharpness,visual distortion,and artifacts.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were quantitatively compared between rFOV-DWI and fFOV-DWI.Using transverse T2-weighted imaging(T2WI)as the anatomi-cal reference,objective metrics reflecting alignment accuracy of lymph nodes on DWI were measured and compared:antero-posterior diameter(AP),left-right diameter(LR),area,and distortion rate(DR).Apparent diffusion coefficient(ADC)values were analyzed,and the sensitivity and specificity were compared between the two groups.Receiver operating character-istic curves were generated to predict malignancy.Results:Interobserver agreement between the two radiologists was excel-lent,with all intraclass correlation coefficients exceeding 0.7.rFOV-DWI demonstrated significantly higher subjective scores than fFOV-DWI in overall image quality,artifacts,and visual distortion(all P<0.05),while no significant difference was observed in sharpness(P=0.296).Significantly higher SNR and CNR values were observed in rFOV-DWI compared to fFOV-DWI(SNR:21.12±13.35 vs 12.85±6.70,CNR:18.43±11.95 vs 11.83±6.37,all P<0.05).Lymph node align-ment accuracy to T2WI was significantly superior with rFOV-DWI,evidenced by non-significant geometric deviations(AP:P=0.330;LR:P=0.088;Area:P=0.060;DR:P=0.079),while fFOV-DWI showed significant mismatches(AP:P<0.001;LR:P<0.001;Area:P=0.003;DR:P=0.015).Significantly lower ADC values were observed in metastatic lymph nodes with rFOV-DWI compared to fFOV-DWI(t=-2.491,P=0.014).However,both techniques demonstrated compara-ble diagnostic performance,as evidenced by area under the curve(0.977 vs 0.920),specificity(83.3％vs 83.3％),and sensitivity(93.1％vs 95.9％)(all P>0.05).Conclusion:In DWI of cervical lymph nodes,rFOV-DWI and fFOV-DWI demonstrated comparable diagnostic performance for detecting metastatic involvement.However,rFOV-DWI significantly im-proved image quality,clearly display lesions,and provide more reliable imaging data for clinical diagnosis.关键词
磁共振成像/弥散加权成像/颈部转移性淋巴结/图像质量/表观扩散系数Key words
Magnetic resonance imaging/Diffusion-weighted imaging/Metastatic cervical lymph nodules/Image quality/Apparent diffusion coefficient分类
医药卫生引用本文复制引用
杨帆,易思琪,邓和平,林礼波,何雅坤..小视野弥散加权成像在头颈部肿瘤转移性颈部淋巴结中的应用价值[J].肿瘤预防与治疗,2025,38(8):696-702,7.基金项目
This study was supported by grants from Science and Technology Department of Sichuan Province(No.2023YFS0157). 四川省科技厅重点研发项目(编号:2023YFS0157) （No.2023YFS0157）
