上海预防医学2025，Vol.37Issue(6)：503-506,4.DOI:10.19428/j.cnki.sjpm.2025.24635
浙江省长兴县农村老年人结核分枝杆菌潜伏感染调查
Investigation of latent tuberculosis infection among the elderly in rural areas of Changxing County,Zhejiang Province
摘要
Abstract
[Objective]To investigate the current status of latent tuberculosis infection(LTBI)among the elderly population in rural areas of Changxing County,Zhejiang Province,and to provide an evidence for the development of LTBI prevention and control measures.[Methods]Between January and May 2024,elderly individuals participating in urban and rural residents'health checkups were screened for Mycobacterium tuberculosis infection using a domestically produced interferon-γ release assay(IGRA)kit.Individuals tested positive by IGRA but without active tuberculosis were classified as LTBI cases.The prevalence of LTBI among the participants was subsequently analyzed.[Results]Among the 6 765 subjects,637 tested positive by IGRA,including one identified active tuberculosis patient,resulting in a LTBI prevalence rate of 9.40%.There was a statistically significant difference in positivity rates across different IGRA methodologies(χ2=35.530,P<0.001).Higher LTBI rate was observed in males,individuals with a history of diabetes mellitus,and those with a history of pulmonary tuberculosis,exhibiting statistically significant differences(χ2=32.401,P<0.001;χ2=5.789,P=0.020;χ2=39.248,P<0.001,respectively.)No statistically significant difference in LTBI rate was found across different age groups(χ2=0.238,P=0.971).[Conclusion]The prevalence of LTBI among the elderly rural residents in Changxing County is relatively low.Male,individuals with a history of diabetes mellitus,and those with a history of pulmonary tuberculosis have an increased risk of LTBI,warranting targeted risk monitoring and timely interventions.关键词
结核分枝杆菌/结核分枝杆菌潜伏感染/农村老年人/γ干扰素释放试验Key words
Mycobacterium tuberculosis/latent tuberculosis infection/rural elderly/interferon-γ release assay分类
医药卫生引用本文复制引用
张健,宋玉芳,任飞林,李雪静,秦家胜,邵斌..浙江省长兴县农村老年人结核分枝杆菌潜伏感染调查[J].上海预防医学,2025,37(6):503-506,4.基金项目
湖州市科技计划项目(2023GY80) （2023GY80）
湖州市疾病预防控制中心科技计划项目(KJJH202403) （KJJH202403）
