上海预防医学2025，Vol.37Issue(6)：507-510,4.DOI:10.19428/j.cnki.sjpm.2025.24552
2019年江西省一家百日咳哨点医院监测病例的流行病学与临床特征
Epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019
摘要
Abstract
[Objective]To analyze the epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019,and to provide corresponding references for the prevention and control of pertussis.[Methods]Case investigation of pertussis was conducted among sentinel hospital surveillance cases,collecting their basic information,epidemiological characteristics,clinical characteristics,and other information.[Results]A total of 125 pertussis surveillance cases were investigated in 2019,including 73 clinically diagnosed cases(58.40%)and 52 confirmed cases(41.60%).The age of onset was mainly concentrated in children under 5 years old(108 cases,86.40%),with the largest number of cases in infants aged less than 1-year-old(48 cases,38.40%).Most cases had a history of receiving pertussis vaccine before onset(110 cases,88.00%),and the intervals between the onset date and the date of last dose of pertussis vaccine in the 1-2 doses group were significantly shorter than that in the 3-4 doses group(U=-5.990,P<0.001).Probable household transmission of pertussis was found in 3 cases.All cases had cough symptoms,mainly manifested as whooping cough(77 cases,61.60%),in addition to other main clinical manifestations,such as fever(76 cases,60.80%),vomiting(30 cases,24.00%),conjunctival congestion(27 cases,21.60%),and inspiratory whoop(16 cases,12.80%).A total of 73 cases(58.40%)experienced complications,including 1 death case.All the cases had multiple medical visit experiences before this visit,with an interval of 2(0,3)days between the onset date and the first visit date.The misdiagnosis rate at the first medical visit was 88.00%(110/125),and the misdiagnosis rate of the first visit in secondary and primary hospitals was significantly higher than that in tertiary hospitals,exhibiting a statistically significant difference(χ2=21.582,P<0.001).[Conclusion]The clinical symptoms of pertussis cases are often atypical,and the first diagnosis is prone to misdiagnosis,so it's necessary to further strengthen the early diagnosis capabilities for pertussis cases in healthcare institutions,especially in the primary healthcare institutions.关键词
百日咳/监测/流行病学/临床特征/误诊Key words
pertussis/surveillance/epidemiology/clinical characteristic/misdiagnosis分类
医药卫生引用本文复制引用
邬辉,刘杰,赵玉芹,郭世成,文海蓉,李剑..2019年江西省一家百日咳哨点医院监测病例的流行病学与临床特征[J].上海预防医学,2025,37(6):507-510,4.基金项目
江西省卫生健康委员会科技计划课题项目(20196004,202311097) （20196004,202311097）
