中国输血杂志2025，Vol.38Issue(8)：1043-1049,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.08.007
ABO血型相容性对肝移植术后早期并发症影响的回顾性分析
Effect of ABO blood group compatibility on early complications after liver transplantation:a retrospective analysis
摘要
Abstract
Objective To analyze the correlation between ABO blood group compatibility and the risk of early compli-cations after liver transplantation,and to identify risk factors for clinical intervention.Methods Clinical data of 404 liver transplant recipients and donors were collected.Based on donor-recipient ABO matching,patients were divided into three groups:ABO-Identical(ABO-Id,n=313),ABO-compatible(ABO-c,n=68),ABO-incompatible(ABO-i,n=23).Clini-cal data,early complications,and associated risk factors were compared.Results Compared with the ABO-Id,ABO-c and ABO-i recipients were younger,had a higher proportion of primary biliary atresia,and more frequently received living-donor transplantation from relatives(P<0.05).Overall complication rates were:ABO-c 47.1%(32/68),ABO-i 43.5%(10/23),ABO-Id 39.3%(123/313),with no significant intergroup difference(P>0.05).Infection was the most common complication[ABO-c 30.9%(21/68),ABO-i 21.7%(5/23),ABO-Id 17.9%(56/313)].No significant differences were found in infection,vascular/biliary or acute kidney injury/renal failure among the three groups(P>0.05).However,ABO-c group had significantly higher rates of ascites/abscess(20.6%vs 8.9%,P<0.05)and pleural effusion(14.7%vs 7.0%,P<0.05)than ABO-Id group.There was no significant difference in the incidence of complications and ABO blood group between ABO non-Identical(ABO-c and ABO-i)and Identical groups.Logistic regression analysis showed that the risk of ascites/abscess in ABO non-Identical was higher than that in ABO-Id liver transplantation(P<0.05),and the risk of ascites/abscess after ABO-c liver transplantation was 2.246 times higher than that of ABO-Id liver transplantation.The pri-mary biliary atresia were a risk factor for postoperative ascites/abscess.Conclusion Enhanced postoperative management is critical for ABO-nonidentical(especially ABO-compatible)recipients,and those with biliary atresia to reduce complica-tion risks.关键词
ABO血型不同但相容/ABO血型不相容/肝移植/早期并发症/腹腔积液/脓肿Key words
ABO-compatible/ABO-incompatible/liver transplantation/early complications/ascites/abscess分类
医药卫生引用本文复制引用
吴学敏,马一鸣,李小飞..ABO血型相容性对肝移植术后早期并发症影响的回顾性分析[J].中国输血杂志,2025,38(8):1043-1049,7.基金项目
国际亚太血型与基因组学协会科研基金项目(IAABG25SR001) （IAABG25SR001）
北京市自然科学基金青年项目(7254324) （7254324）
