中国输血杂志2025，Vol.38Issue(8)：1071-1076,6.DOI:10.13303/j.cjbt.issn.1004-549x.2025.08.011
2020-2023年献血者晕厥性血管迷走神经反应多中心监测结果分析
Analysis of syncopal DRVR in blood donors:multicenter hemovigilance data(2020-2023)
摘要
Abstract
Objective Data on syncopal donation-related vasovagal reaction(DRVR)collected from 74 blood centers between 2020 and 2023 was statistically analyzed to provide a reference for developing preventive strategies against syncopal DRVR.Methods Data on blood donation adverse reactions and basic information of donors from 2020 to 2023 were col-lected through the information management system at monitoring sentinel sites.Statistical analysis was performed on the fol-lowing aspects of syncopal DRVR:characteristics of donors who experienced syncope,reported incidence,triggers,dura-tion,presence and occurrence time of syncope-related trauma,clinical management including outpatient and inpatient treat-ment,and severity grading.Results From 2020 to 2023,45 966 donation-related adverse reactions were recorded.Of these,1 665(3.72%)cases were syncopal DRVR.The incidence of syncopal DRVR decreased with age,being the highest in the 18-22 age group.Incidence was significantly higher in female donors than male donors,in first-time donors than re-peat donors,and in university and individual donors than group donors(all P<0.05).There was no statistically significant difference among different blood donation locations(P>0.05).The top three triggers were tension,fatigue,and needle phobia or fear of blood.Among syncopal DRVR cases,60.36%occurred during blood collection,87.63%lasted for less than 60 seconds,and 5.05%were accompanied by trauma.Notably,57.14%of these traumas occurred after donor had left the blood collection site.Syncope severity was graded based on required treatment:grade 1(fully recovered without treat-ment,95.50%);grade 2(recovered after outpatient treatment,4.02%);and grade 3(recovered after inpatient treat-ment,0.48%).Conclusion By analyzing the data of syncopal DRVR cases,it is possible to provide a reference for for-mulating blood donor safety policies.关键词
献血者安全监测/献血不良反应/献血相关血管迷走神经反应/晕厥/严重程度/多中心监测Key words
donor hemovigilance/blood donation adverse reaction/donation related vasovagal reaction/syncope/se-verity/multicentre monitoring分类
医药卫生引用本文复制引用
杨俊鸿,冯国强,郭晓婕,曾嘉,黄霞,徐庆,朱文钦,唐飞,何汝汝,卢珍萍,叶柱江,钟发德,吴刚..2020-2023年献血者晕厥性血管迷走神经反应多中心监测结果分析[J].中国输血杂志,2025,38(8):1071-1076,6.基金项目
重庆市九龙坡区科技计划项目(2023-02-037-Z) （2023-02-037-Z）
重庆市输血协会华兰生物科研基金(No.CQSX-HL-201401) （No.CQSX-HL-201401）
