摘要
Abstract
Objective To compare the clinical efficacy and economic efficiency of Paracetamol,Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Tablets(Ⅱ)/Paracetamol,Pseudoephedrine Hydrochloride and Diphenhydramine Hydrochloride Tablets(trade name:Danuo)with Paracetamol,Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Tablets(Ⅱ)Paracetamol,Pseudoephedrine Hydrochloride,Diphenhydramine Hydrochloride and Dextromethorphan Hydrobromide Tablets(trade name:Bai Jia Hei)in the treatment of colds.Methods Based on randomized controlled clinical trials of Danuo and Bai Jia Hei,a decision tree model was constructed to conduct a cost-effectiveness analysis from the health system perspective.The effect parameter was the clinical control rate(derived from trial data),and the cost parameter was drug treatment cost.Incremental cost-effectiveness ratio(ICER)was calculated,followed by sensitivity analysis.Results Cost-effectiveness analysis showed that,compared with Bai Jia Hei,Danuo increased the clinical control rate by 4.38%while raising treatment costs by 15.12 CNY.Using China's 2023 per capita disposable income(39,218 CNY)as the reference threshold,the ICER was less than 0.009%of per capita income.Conclusion For cold treatment,Danuo demonstrates superior clinical control rates to Bai Jia Hei.When the willingness-to-pay threshold exceeds the corresponding ICER value,Danuo is more cost-effective.关键词
氨酚伪麻美芬片(Ⅱ)与苯酚伪麻片/达诺/感冒/药物经济学Key words
Paracetamol,Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Tablets(Ⅱ)/Paracetamol,Pseudoephedrine Hydrochloride and Diphenhydramine Hydrochloride Tablets/Danuo/Colds/Pharmacoeconomics分类
医药卫生
