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首页|期刊导航|Bone Research|AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

Keyu Kong Li Liu Renfang Zhang Yongyun Chang Yueming Shao Chen Zhao Hua Qiao Minghao Jin Xuzhuo Chen Wentao Shi Xinru Wu Wenxuan Fan Yuehao Hu Kewei Rong Pu Zhang Baixing Li Jingwei Zhang Peixiang Ma Xiaoling Zhang Huiwu Li Zanjing Zhai

Bone Research2025,Vol.13Issue(4):P.987-1000,14.
Bone Research2025,Vol.13Issue(4):P.987-1000,14.DOI:10.1038/s41413-025-00431-2

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

Keyu Kong 1Li Liu 2Renfang Zhang 2Yongyun Chang 1Yueming Shao 2Chen Zhao 1Hua Qiao 1Minghao Jin 1Xuzhuo Chen 3Wentao Shi 4Xinru Wu 1Wenxuan Fan 1Yuehao Hu 1Kewei Rong 1Pu Zhang 1Baixing Li 1Jingwei Zhang 1Peixiang Ma 1Xiaoling Zhang 5Huiwu Li 1Zanjing Zhai1

作者信息

  • 1. Shanghai Key Laboratory of Orthopaedic Implants,Department of Orthopaedic Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,China
  • 2. Department of Infection and Immunity,Shanghai Public Health Clinical Center(SPHCC),Fudan University,Shanghai,China
  • 3. Shanghai Key Laboratory of Stomatology,Department of Oral Surgery,College of Stomatology,Ninth People’s Hospital,Shanghai Research Institute of Stomatology,National Clinical Research Center of Stomatology,Shanghai Jiao Tong University School of Medicine,Shanghai,China
  • 4. Department of Biostatistics in Clinical Research Unit,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,China
  • 5. Department of Orthopedic Surgery,Xinhua Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai,China
  • 折叠

摘要

关键词

antiviral regimesprotease inhibitors pis stand/acquired immune deficiency syndrome aids patients/Knee OA/Lopinavir/antiviral agents/AIDS/HIV/Osteoarthritis

分类

临床医学

引用本文复制引用

Keyu Kong,Li Liu,Renfang Zhang,Yongyun Chang,Yueming Shao,Chen Zhao,Hua Qiao,Minghao Jin,Xuzhuo Chen,Wentao Shi,Xinru Wu,Wenxuan Fan,Yuehao Hu,Kewei Rong,Pu Zhang,Baixing Li,Jingwei Zhang,Peixiang Ma,Xiaoling Zhang,Huiwu Li,Zanjing Zhai..AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition[J].Bone Research,2025,13(4):P.987-1000,14.

基金项目

supported by Natural Science Foundation of China(82472476) (82472476)

Fundamental Research Funds for the Central Universities(YG2023ZD15) (YG2023ZD15)

The Youth Talent Program from Shanghai Health System(2022YQ020) (2022YQ020)

AI-Driven Reform of Research Paradigms Empowers Discipline Advancement Initiatives from Shanghai Municipal Education Commission(Grant No.JWAIZD-7) (Grant No.JWAIZD-7)

the Natural Science Foundation of Shanghai(23ZR1437300). (23ZR1437300)

Bone Research

2095-4700

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