首页|期刊导航|Bone Research|Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis

Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis

Zhenyu Zhang Lulu Liu Huibo Ti Minnan Chen Yuechun Chen Deyan Du Wenjing Zhan Tongtong Wang Xian Wu Junjie Wu Dong Mao Zhengdong Yuan Jingjing Ruan Genxiang Rong Feng-lai Yuan

Bone Research2025，Vol.13Issue(4)：P.968-986,19.

Bone Research2025，Vol.13Issue(4)：P.968-986,19.DOI:10.1038/s41413-025-00430-3

Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis

Zhenyu Zhang ¹Lulu Liu ²Huibo Ti ¹Minnan Chen ³Yuechun Chen ¹Deyan Du ⁴Wenjing Zhan ⁵Tongtong Wang ¹Xian Wu ¹Junjie Wu ¹Dong Mao ⁶Zhengdong Yuan ¹Jingjing Ruan ⁷Genxiang Rong ⁸Feng-lai Yuan¹

作者信息

1. Institute of Integrated Chinese and Western Medicine,Affiliated Hospital of Jiangnan University,Jiangsu,China
2. Biomedical engineering facility of National Infrastructures for Translational Medicine,State Key Laboratory of Complex Severe and Rare Diseases in Peking Union Medical College Hospital,Chinese Academy of Medical Science and Peking Union Medical College,Beijing,China
3. Nantong First People’s Hospital,Nantong,China
4. The Key Laboratory of Synthetic and Biological Colloids,Ministry of Education,School of Chemical and Material Engineering,Jiangnan University,Wuxi,China
5. The Key Laboratory of Anti-Inflammatory and Immune Medicine,Ministry of Education,Anhui Medical University,Hefei,China
6. Orthopaedic Institute,Wuxi 9th People’s Hospital Affiliated to Soochow University,Wuxi,China
7. Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of Anhui Medical University,Hefei,China
8. Department of Orthopedics,The First Affiliated Hospital of Anhui Medical University,Hefei,China
折叠

摘要

关键词

Rheumatoid Arthritis/rheumatoid arthritis ra/Small Extracellular Vesicles/miR/proinflammatory mediators/Synovial Fibroblasts/synovial fibroblasts sfs maintain/systemic autoimmune disease

分类

临床医学

引用本文复制引用

Zhenyu Zhang,Lulu Liu,Huibo Ti,Minnan Chen,Yuechun Chen,Deyan Du,Wenjing Zhan,Tongtong Wang,Xian Wu,Junjie Wu,Dong Mao,Zhengdong Yuan,Jingjing Ruan,Genxiang Rong,Feng-lai Yuan..Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis[J].Bone Research,2025,13(4):P.968-986,19.

基金项目

the National Natural Science Foundation of China(82372412) （82372412）

the Social Development Project of Jiangsu Province(BE2022701) （BE2022701）

the Top Talent Support Program for Young and Middle-aged People of the Wuxi Health Committee(BJ2020044,BJ2020057,HB2020043) （BJ2020044,BJ2020057,HB2020043）

the Fundamental Research Funds of the Health and Family Planning Commission of Wuxi(M202024) （M202024）

the Special Program for Translational Medicine Research of the Wuxi Translational Medicine Center(2020DHYB07,2020DHYB03) （2020DHYB07,2020DHYB03）

the Key Special Project of Precision Medicine of the Wuxi Health Commission(J202101) （J202101）

peking union medical college hospital talent cultivation program(UHB50192). （UHB50192）

Bone Research

ISSN：2095-4700

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