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RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth

Shawn A.Hallett Ashley Dixon Isabella Marrale Lena Batoon JoséBrenes Annabelle Zhou Ariel Arbiv Vesa Kaartinen Benjamin Allen Wanida Ono Renny T.Franceschi Noriaki Ono

Bone Research2025，Vol.13Issue(4)：P.939-956,18.

Bone Research2025，Vol.13Issue(4)：P.939-956,18.DOI:10.1038/s41413-025-00426-z

RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth

Shawn A.Hallett ¹Ashley Dixon ¹Isabella Marrale ¹Lena Batoon ¹JoséBrenes ¹Annabelle Zhou ¹Ariel Arbiv ¹Vesa Kaartinen ²Benjamin Allen ³Wanida Ono ⁴Renny T.Franceschi ¹Noriaki Ono⁵

作者信息

1. Department of Periodontics and Oral Medicine,University of Michigan School of Dentistry,Ann Arbor,MI,USA
2. Department of Biological and Materials Sciences and Prosthodontics,University of Michigan School of Dentistry,Ann Arbor,MI,USA
3. Department of Cell and Developmental Biology,University of Michigan Medical School,Ann Arbor,MI,USA
4. Department of Orthodontics,University of Texas Health Science Center at Houston School of Dentistry,Houston,TX,USA
5. Department of Diagnostic and Biomedical Sciences,University of Texas Health Science Center at Houston School of Dentistry,Houston,TX,USA
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摘要

关键词

cranial base synchondroses/chondrocyte proliferation/hypertrophy/cleidocranial dysplasia/cranial base synchondrosescomprised/apoptosis/inactivated runx/RUNX

分类

临床医学

引用本文复制引用

Shawn A.Hallett,Ashley Dixon,Isabella Marrale,Lena Batoon,JoséBrenes,Annabelle Zhou,Ariel Arbiv,Vesa Kaartinen,Benjamin Allen,Wanida Ono,Renny T.Franceschi,Noriaki Ono..RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth[J].Bone Research,2025,13(4):P.939-956,18.

基金项目

National Institutes of Health grant F30DE030675(S.A.H.) （S.A.H.）

National Institutes of Health grant T32DE007057(S.A.H.) （S.A.H.）

University of Michigan Rackham Graduate School Pre-Candidate Research Grant(S.A.H.) （S.A.H.）

University of Michigan Rackham Graduate School Candidate Research Grant(S.A.H.) （S.A.H.）

National Institutes of Health grant R35DE034348(N.O.) （N.O.）

National Institutes of Health grant R01DE026666(N.O.) （N.O.）

National Institutes of Health grant R01DE030630(N.O.) （N.O.）

National Institutes of Health grant R01DE029465(R.T.F.) （R.T.F.）

Department of Defense grant W81XWH2010571(R.T.F.) （R.T.F.）

National Institutes of Health grant P30 AR069620(The Michigan Integrative Musculoskeletal.Health Core Center). （The Michigan Integrative Musculoskeletal.Health Core Center）

Bone Research

ISSN：2095-4700

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