黑龙江动物繁殖2025，Vol.33Issue(4)：61-66,6.DOI:10.19848/j.cnki.ISSN1005-2739.2025.08.0010
脂质代谢对动物卵母细胞成熟和胚胎发育的影响
Effects of lipid metabolism on animal oocyte maturation and embryo development
摘要
Abstract
As research in metabolomics and reproductive biology continues to advance,lipid metabolism—a crucial component of cellular metabolism—has garnered significant attention for its role in germ cell development.Lipid metabolism provides energy to oocytes and embryos through fatty acid oxidation and triglyceride breakdown,and it also participates in biomembrane construction and signal transduction.Signaling pathways such as AMPK,mTOR and PPAR regulate lipid synthesis,breakdown and utilization to maintain cellular energy homeostasis.Additionally,abnormal lipid metabolism may lead to female reproductive disorders.This review summarizes the effects of lipid metabolism on the maturation of bovine and ovine oocytes and early embryonic development,as well as its applications in assisted reproductive technologies,aiming to provide innovative perspectives and strategic approaches for enhancing in vitro embryo production and elevating the efficacy of assisted reproductive technologies.关键词
脂质代谢/脂滴/卵母细胞成熟/早期胚胎发育/辅助生殖技术Key words
lipid metabolism/lipid droplets/oocyte maturation/early embryonic development/assisted reproductive technology分类
生物科学引用本文复制引用
刘志娇,马子豪,胡广东,万鹏程..脂质代谢对动物卵母细胞成熟和胚胎发育的影响[J].黑龙江动物繁殖,2025,33(4):61-66,6.基金项目
新疆生产建设兵团重点领域科技攻关项目(2024AB017) （2024AB017）
国家绒毛用羊产业技术体系项目(CARS-39-07) （CARS-39-07）
新疆维吾尔自治区"天山英才"培养计划青年科技拔尖人才项目(2022TSYCCX0124) （2022TSYCCX0124）
