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Physiologically relevant coculture model for oral microbial-host interactions

Zeyang Pang Nicole M.Cady Lujia Cen Thomas M.Schmidt Xuesong He Jiahe Li

国际口腔科学杂志（英文版）2025，Vol.17Issue(4)：517-528,12.

国际口腔科学杂志（英文版）2025，Vol.17Issue(4)：517-528,12.DOI:10.1038/s41368-025-00365-9

Physiologically relevant coculture model for oral microbial-host interactions

Zeyang Pang ¹Nicole M.Cady ²Lujia Cen ³Thomas M.Schmidt ⁴Xuesong He ³Jiahe Li¹

作者信息

1. Department of Biomedical Engineering,College of Engineering and School of Medicine,University of Michigan,Ann Arbor,MI,USA
2. Department of Microbiology and Immunology,University of Michigan Medical School,Ann Arbor,MI,USA
3. Department of Microbiology,The ADA Forsyth Institute,Somerville,MA,USA
4. Department of Microbiology and Immunology,University of Michigan Medical School,Ann Arbor,MI,USA||Department of Internal Medicine,University of Michigan,Ann Arbor,MI,USA||Department of Ecology and Evolutionary Biology,University of Michigan,Ann Arbor,MI,USA
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摘要

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Zeyang Pang,Nicole M.Cady,Lujia Cen,Thomas M.Schmidt,Xuesong He,Jiahe Li..Physiologically relevant coculture model for oral microbial-host interactions[J].国际口腔科学杂志（英文版）,2025,17(4):517-528,12.

基金项目

This work was supported by National Science Foundation CAREER(2238972)and National Institute of Dental and Craniofacial Research awards(R03DE031329 and R01DE030943).We thank the Translational Tissue Modeling Laboratory and the Microscopy Core at the University of Michigan,Ann Arbor,for their valuable support.We are especially grateful to Binyamin Jacobovitz from the Microscopy Core for his assistance with confocal microscopy equipment and training.We also extend our thanks to Michael K.Dame,Jack Morgan,and Dominic Tigani from the Translational Tissue Modeling Laboratory for their expert training and insightful suggestions on cell monolayer preparation techniques.The Translational Tissue Modeling Laboratory is supported by the University of Michigan(Center for Gastrointestinal Research,Office of the Dean,Comprehensive Cancer Center,and the Departments of Pathology,Pharmacology,and Internal Medicine)with additional funding from the Endowment for Basic Sciences. （2238972）

国际口腔科学杂志（英文版）

ISSN：1674-2818

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